Zhang Na, Cheng Lei, Chen Min, Chen Jian, Yang Yue, Xie Ming, Li Cai, Chen Xiao-Ling, Zhou Liang, Wu Hai-Tao
a Department of Otolaryngology Head and Neck Surgery , First Central Hospital, Otorhinolaryngology Institute of Tianjin , Tianjin , China.
b Department of Otolaryngology-Head and Neck Surgery , EENT Hospital, Fudan University , Shanghai , China.
Acta Otolaryngol. 2017 Nov;137(11):1199-1203. doi: 10.1080/00016489.2017.1347826. Epub 2017 Jul 14.
To explore the relationship between the morphological characteristics and pathological diagnosis of vocal cords leukoplakia.
A total of 1635 vocal cords were collected. The morphology were classified into three types (Type I, II, III): flat and smooth; bulge and smooth; bulge and rough. The pathological reports were classified into five groups: no dysplasia, mild dysplasia, moderate dysplasia, severe dysplasia and cancerization. The number of the patients or vocal cords in each type and group was counted and their ratio was compared.
In Type I, the number of vocal cord in Group A group was 2.2 and 2.6 times of the one in Type II and Type III respectively. In Type II, the mild, moderate dysplasia ratio was higher than those in Type I. In Type III group the ratio of severe dysplasia was 2.6 and 5.5 times of the one in Type II and Type I respectively. The ratio of Group E in Type III was 2.7 and 7.9 times of the one of Type II and Type I. The result was significant (pearson Chi-square value was 517.6, p = .00).
The pathological results of vocal cord leukoplakia can be evaluated by morphology in most cases.
探讨声带白斑的形态学特征与病理诊断之间的关系。
共收集1635条声带。形态学分为三种类型(I型、II型、III型):扁平光滑型;隆起光滑型;隆起粗糙型。病理报告分为五组:无发育异常、轻度发育异常、中度发育异常、重度发育异常和癌变。统计各类型和组别的患者或声带数量,并比较其比例。
在I型中,A组声带数量分别是II型和III型的2.2倍和2.6倍。在II型中,轻度、中度发育异常比例高于I型。在III型组中,重度发育异常比例分别是II型和I型的2.6倍和5.5倍。III型中E组比例分别是II型和I型的2.7倍和7.9倍。结果具有显著性(Pearson卡方值为517.6,p = 0.00)。
大多数情况下,声带白斑的病理结果可通过形态学进行评估。