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兔情绪应激时血清游离脂肪酸水平及体温变化。羟化二烯的作用。

Serum free fatty acid level and body temperature changes in emotional stress in rabbits. Effect of hydroxydial.

作者信息

Wasilewska J

出版信息

Acta Physiol Pol. 1978 Nov-Dec;29(6):589-92.

PMID:34315
Abstract

Fourteen New Zealand rabbits were immobilized for 75 minutes During this time the ear (Te) and rectal (Tre) temperatures were measured at 5 min intervals. Immediately before immobilization, and then in the 35th, 55th, and 75th min of immobilization blood samples were taken for determinations of the serum free fatty acid (FFA) levels. A statistically significant fall of Tre and a significant rise in the serum FFA levels were observed at the end of immobilization. The ear temperature in these animals exceeded considerably the values as normal. Intravenous administration of hydroxydial 0.1 mg/kg before repeated immobilization prevented body temperature changes and blood FFA level rise in half the animals. In the remaining animals the changes became more intensive. It is supposed that the tested rabbits differed in their reactivity to stressful stimuli, and this hypothesis was confirmed by experiments in which weaker stimuli were used. Repetition of stressful stimuli increased the intensity of these autonomic responses in all animals.

摘要

十四只新西兰兔被固定75分钟。在此期间,每隔5分钟测量一次耳部(Te)和直肠(Tre)温度。在固定前即刻,以及在固定的第35、55和75分钟采集血样,用于测定血清游离脂肪酸(FFA)水平。在固定结束时,观察到Tre有统计学意义的下降以及血清FFA水平显著升高。这些动物的耳部温度大大超过正常数值。在重复固定前静脉注射0.1mg/kg的羟基二烯丙基巴比妥,可防止半数动物体温变化和血液FFA水平升高。在其余动物中,这些变化变得更加剧烈。据推测,受试兔子对压力刺激的反应性存在差异,这一假设通过使用较弱刺激的实验得到了证实。重复压力刺激会增加所有动物这些自主反应的强度。

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