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选择性背根切断术治疗痉挛性脑瘫的手术结果

Surgical Results of Selective Dorsal Rhizotomy for the Treatment of Spastic Cerebral Palsy.

作者信息

Volpon Santos Marcelo, Carneiro Vinicius M, Oliveira Patricia N B G C, Caldas Carla A T, Machado Helio R

机构信息

Division of Pediatric Neurosurgery, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.

Department of Neurorehabilitation, Lucy Montoro Rehabilitation Center, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.

出版信息

J Pediatr Neurosci. 2021 Jan-Mar;16(1):24-29. doi: 10.4103/jpn.JPN_26_20. Epub 2021 Jun 25.

Abstract

BACKGROUND

Selective dorsal rhizotomy (SDR) is one of the surgical alternatives for treating spasticity, especially in children with spastic diplegia secondary to cerebral palsy (CP). It is becoming increasingly used, and the results of this operation need to be further highlighted.

AIM

The main objective of this article was to present the results of such surgical procedure in a cohort of a specialized center, with a particular focus on a quantitative analysis (goniometry).

MATERIALS AND METHODS

Retrospective review of the medical records and gait analyses of a cohort of 34 patients diagnosed with CP submitted to elective SDR at our institution, in a period of 6 years, was carried out. All patients underwent a thorough clinical and neurological assessment, gait analysis at a dedicated laboratory, and magnetic resonance imaging of whole neuro-axis.

STATISTICAL ANALYSIS

For continuous quantitative variables (goniometric angles and muscle tone), a -student test was used. A scatterplot regression analysis was used for the comparison of modified Ashworth scale (mAS) scores and goniometry measurements.

RESULTS AND CONCLUSION

In a mean follow-up of 3.2 years, SDR provides a measurable and consistent improvement in the motor function of spastic patients, as per range of motion and tonus scales, with low complication rates. It also allows for patients to reduce their use of muscle relaxants, even though their global mobility does not change significantly. Therefore, it should be considered for CP patients who suffer with the deleterious effects of spasticity.

摘要

背景

选择性脊神经后根切断术(SDR)是治疗痉挛的手术选择之一,尤其适用于继发于脑瘫(CP)的痉挛性双侧瘫患儿。该手术的应用越来越广泛,其手术效果需要进一步凸显。

目的

本文的主要目的是展示在一个专业中心队列中该手术的效果,特别关注定量分析(角度测量)。

材料与方法

对我院6年间接受选择性SDR手术的34例诊断为CP的患者队列的病历和步态分析进行回顾性研究。所有患者均接受了全面的临床和神经学评估、在专门实验室进行的步态分析以及全神经轴的磁共振成像。

统计分析

对于连续定量变量(角度测量值和肌张力),采用t检验。使用散点图回归分析比较改良Ashworth量表(mAS)评分和角度测量值。

结果与结论

平均随访3.2年,SDR根据运动范围和肌张力量表,在痉挛患者的运动功能方面提供了可测量且持续的改善,并发症发生率低。即使患者的整体活动能力没有显著变化,该手术也能使患者减少肌肉松弛剂的使用。因此,对于受痉挛有害影响的CP患者应考虑采用该手术。

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