Jeffery Samuel M T, Markia Balázs, Pople Ian K, Aquilina Kristian, Smith Jenny, Mohamed Amr Z, Burchell Alison, Jenkins Lyn, Walsh Peter, Clark Natasha, Sacree Jenny, Cramp Mary, Babiker Mohamed O E, Atherton William Guy, Clarke Anna, Edwards Richard J
Department of Neurosurgery, Bristol Royal Hospital for Children, University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom; Department of Neurosurgery, North Bristol NHS Trust, Bristol, United Kingdom; South West Neurosurgery Centre, Derriford Hospital, University Hospitals Plymouth NHS Trust, Plymouth, Devon, United Kingdom.
Department of Neurosurgery, Bristol Royal Hospital for Children, University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom; National Institute for Clinical Neurosciences, Budapest, Hungary.
World Neurosurg. 2019 May;125:e60-e66. doi: 10.1016/j.wneu.2018.12.187. Epub 2019 Jan 16.
Selective dorsal rhizotomy (SDR) is used to improve spasticity, gait, and pain in children with spastic diplegia. There is growing evidence supporting its long-term benefits in terms of functional outcomes, independence, and quality of life. There is, however, little contemporary work describing the surgical morbidity of this irreversible procedure. The purpose of this study is to evaluate the surgical outcomes and complications of SDR at a single United Kingdom center.
Demographics, surgical, postoperative, and follow-up data for all patients undergoing SDR between 2011 and 2016 were collected from medical records.
Preoperative Gross Motor Function Classification System levels in 150 consecutive patients were II (35%), III (65%), and IV (1%). Median age was 6 years and 58% were male patients. There were no deaths, cerebrospinal fluid leaks, returns to theater, or readmissions within 30 days. There were no new motor or sphincter deficits. Postoperative neuropathic pain was reported by 5.3% and sensory symptoms by 8.7%. Other complications included: postoperative nausea and vomiting (19.3%), superficial wound infection (3.3%), urinary retention (1.3%), headache (6.7%), and urine or chest infection (4.7%). Follow-up data were available for all patients (93% to 12 months, 72% to 24 months). Persistent neuropathic symptoms were reported in 6.5% at 24 months.
SDR using a single-level approach is a safe procedure with low surgical morbidity. This study complements the growing evidence base in support of SDR for spastic diplegia and should help inform decisions when considering treatment options.
选择性背根切断术(SDR)用于改善痉挛型双瘫患儿的痉挛、步态和疼痛。越来越多的证据支持其在功能结局、独立性和生活质量方面的长期益处。然而,目前几乎没有当代研究描述这种不可逆手术的手术并发症。本研究的目的是评估英国一家中心SDR的手术结局和并发症。
收集2011年至2016年间所有接受SDR患者的人口统计学、手术、术后和随访数据,数据来源于病历。
连续150例患者术前粗大运动功能分类系统水平为Ⅱ级(35%)、Ⅲ级(65%)和Ⅳ级(1%)。中位年龄为6岁,男性患者占58%。30天内无死亡、脑脊液漏、重返手术室或再次入院情况。无新的运动或括约肌功能缺损。术后有5.3%的患者报告有神经性疼痛,8.7%的患者有感觉症状。其他并发症包括:术后恶心和呕吐(19.3%)、浅表伤口感染(3.3%)、尿潴留(1.3%)、头痛(6.7%)以及泌尿系统或肺部感染(4.7%)。所有患者均有随访数据(93%随访至12个月,72%随访至24个月)。24个月时,6.5%的患者报告有持续性神经性症状。
采用单节段入路的SDR是一种安全的手术,手术并发症发生率低。本研究补充了越来越多支持SDR治疗痉挛型双瘫的证据基础,有助于在考虑治疗方案时提供决策依据。