针对帕金森病和图雷特综合征，靶向苍白球内侧部的脑深部电刺激。
Deep brain stimulation targeting the Globus pallidus internus for Parkinson's disease and Tourette syndrome.
作者信息
Zhang Qiang, Thomsen Teri R
机构信息
Department of Neurology, University of Iowa Hospitals and Clinics, 200 Hawkins Dr., Iowa City, IA, United States of America.
Physician Scientist Training Program, University of Iowa School of Medicine, 200 Hawkins Dr., Iowa City, IA, United States of America.
出版信息
Clin Park Relat Disord. 2020 Oct 16;3:100077. doi: 10.1016/j.prdoa.2020.100077. eCollection 2020.
Abstract
We present a case with co-existing Parkinson's disease and Tourette syndrome. Patient takes aripiprazole for Tourette syndrome, which unfortunately worsens his parkinsonian symptoms. We placed deep brain stimulation targeting the Globus pallidus internus. Strikingly, his parkinsonian motor symptoms and his tics are both well controlled with deep brain stimulation.
摘要
我们报告一例同时患有帕金森病和图雷特综合征的病例。患者因图雷特综合征服用阿立哌唑，但不幸的是，这加重了他的帕金森症状。我们对内侧苍白球进行了深部脑刺激。令人惊讶的是，深部脑刺激使他的帕金森运动症状和抽动症状都得到了很好的控制。
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本文引用的文献
1
Asymmetric Drug-Induced Parkinsonism and Psychopathology: A Prospective Naturalistic Study in Long-Stay Psychiatric Patients.不对称性药物性帕金森综合征与精神病理学：一项针对长期住院精神科患者的前瞻性自然主义研究。
Front Psychiatry. 2018 Feb 5;9:18. doi: 10.3389/fpsyt.2018.00018. eCollection 2018.
2
Simultaneous improvement of tics and parkinsonism after pallidal DBS.苍白球深部脑刺激术后抽动症状和帕金森病症状同时改善。
Parkinsonism Relat Disord. 2014 Sep;20(9):1022-3. doi: 10.1016/j.parkreldis.2014.05.009. Epub 2014 Jun 2.
3
Development of Parkinsonism following exposure to aripiprazole: two case reports.阿立哌唑暴露后帕金森症的发生：两例病例报告。
J Med Case Rep. 2009 Mar 10;3:6448. doi: 10.1186/1752-1947-3-6448.
4
Therapy-refractory Tourette syndrome: beneficial outcome with globus pallidus internus deep brain stimulation.难治性抽动秽语综合征：内侧苍白球脑深部电刺激治疗效果良好
Mov Disord. 2008 Jul 15;23(9):1300-2. doi: 10.1002/mds.21930.
5
Aripiprazole-induced parkinsonism and its association with dopamine and serotonin receptor polymorphisms.
J Clin Psychopharmacol. 2008 Jun;28(3):352-3. doi: 10.1097/JCP.0b013e318172757f.
6
GPi deep brain stimulation for Tourette syndrome improves tics and psychiatric comorbidities.苍白球腹内侧核深部脑刺激治疗抽动秽语综合征可改善抽动症状和精神共病。
Neurology. 2007 Jan 9;68(2):159-60. doi: 10.1212/01.wnl.0000250354.81556.90.
7
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