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一例罕见的疯蜜病病例:完全性心脏传导阻滞的可逆病因

A Rare Case of Mad Honey Disease: A Reversible Cause of Complete Heart Block.

作者信息

Setareh-Shenas Saman, Kaplin Scott, Bania Theodore C, Kornberg Robert

机构信息

Mount Sinai Heart, Icahn School of Medicine at Mount Sinai, St. Luke's Hospital and Mount Sinai West Hospital, New York, New York.

Department of Medicine, Icahn School of Medicine at Mount Sinai, St. Luke's Hospital and Mount Sinai West Hospital, New York.

出版信息

JACC Case Rep. 2019 Nov 13;1(4):579-582. doi: 10.1016/j.jaccas.2019.09.015. eCollection 2019 Dec.

DOI:10.1016/j.jaccas.2019.09.015
PMID:34316883
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8288791/
Abstract

This case describes a patient with hypotension, bradycardia, and third-degree atrioventricular block following ingestion of a grayanotoxin-containing species, or lily of the valley bush. Although unlikely in metropolitan environments, physicians should be aware of the possibility of grayanotoxin ingestion when confronted with new-onset heart block even in nonendemic areas. ().

摘要

本病例描述了一名患者,在摄入含灰藜毒素的物种或铃兰灌木后出现低血压、心动过缓和三度房室传导阻滞。尽管在大都市环境中不太可能发生,但即使在非流行地区,医生在面对新发心脏传导阻滞时也应意识到摄入灰藜毒素的可能性。()

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本文引用的文献

1
Grayanotoxin poisoning: 'mad honey disease' and beyond.格叶榕毒素中毒:“疯蜜病”及其他。
Cardiovasc Toxicol. 2012 Sep;12(3):208-15. doi: 10.1007/s12012-012-9162-2.
2
Cardiac effects of "mad honey": a case series.“疯蜜”的心脏毒性:病例系列研究。
Clin Toxicol (Phila). 2010 Jul;48(6):528-32. doi: 10.3109/15563650.2010.497150.
3
Chronic mad honey intoxication syndrome: a new form of an old disease?
Europace. 2009 Jul;11(7):954-6. doi: 10.1093/europace/eup126. Epub 2009 Jun 5.
蜂产品作为预防和治疗常见心血管疾病的有趣天然药物。
Nutrients. 2022 May 28;14(11):2267. doi: 10.3390/nu14112267.