Cox J D
Radiology. 1978 Mar;126(3):767-72. doi: 10.1148/126.3.767.
Total central lymphatic irradiation (2500-3000 rads in 3 to 6 weeks) including the entire abdomen, the supradiaphragmatic nodal areas, and Waldeyer's ring is being investigated as a potentially curative approach to patients with Stage III disease. Twenty-two patients have been treated (24-month minimum observation). All evidence of disease has disappeared in every patient. Three patients have developed local recurrence; 2 of them received 2000 rads or less. Three patients had marginal recurrences, and 5 developed generalized disease involving viscera. Fourteen patients (64%) are alive and free of any evidence of disease from 24-90 months (median, 54 months). Absolute survival is 82% (18/22).
正在研究对Ⅲ期疾病患者采用全中枢淋巴系统照射（3至6周内给予2500 - 3000拉德），包括整个腹部、膈上淋巴结区域和瓦尔代尔环，作为一种潜在的治愈方法。已治疗22例患者（至少观察24个月）。所有患者的疾病证据均已消失。3例患者出现局部复发；其中2例接受的照射剂量为2000拉德或更低。3例患者出现边缘复发，5例发展为涉及内脏的全身性疾病。14例患者（64%）存活，24至90个月内无任何疾病证据（中位数为54个月）。绝对生存率为82%（18/22）。
