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使用塔非酰胺治疗的心脏淀粉样变性的首次随访,通过骨闪烁显像的绝对定量评估

First Follow-Up of Cardiac Amyloidosis Treated by Tafamidis, Evaluated by Absolute Quantification in Bone Scintigraphy.

作者信息

Bellevre Dimitri, Bailliez Alban, Maréchaux Sylvestre, Manrique Alain, Mouquet Frédéric

机构信息

Department of Cardiology, Normandy University, Caen, France.

Department of Nuclear Medicine, Lille Catholic Institute Hospital Group, Lomme, France.

出版信息

JACC Case Rep. 2021 Jan 20;3(1):133-135. doi: 10.1016/j.jaccas.2020.11.036. eCollection 2021 Jan.

Abstract

Assessment of absolute myocardial hydroxydimethylene diphosphonate-technetium-99m uptake using standardized uptake value with a single-photon emission computed tomography-computed tomography cadmium zinc telluride camera (Discovery NM/CT 670CZT, GE Healthcare, Chicago, Illinois) in a patient with cardiac transthyretin-related amyloidosis treated with tafamidis showed a decrease in hydroxydimethylene diphosphonate cardiac uptake. This imaging technique should be helpful in monitoring therapy and evaluating prognosis. ().

摘要

在一名接受塔非米地治疗的心脏转甲状腺素蛋白相关淀粉样变性患者中,使用标准化摄取值,通过单光子发射计算机断层扫描-计算机断层扫描碲化镉锌相机(Discovery NM/CT 670CZT,GE医疗集团,伊利诺伊州芝加哥)评估心肌羟基二亚甲基二膦酸盐-锝-99m的绝对摄取量,结果显示心肌羟基二亚甲基二膦酸盐摄取量降低。这种成像技术应有助于监测治疗和评估预后。()

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d62d/8305621/4a85b83cd781/fx1.jpg

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