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Structure and analysis of nanobody binding to the human ASIC1a ion channel.
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Mambalgin-1 pain-relieving peptide locks the hinge between α4 and α5 helices to inhibit rat acid-sensing ion channel 1a.
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The receptor site of the spider toxin PcTx1 on the proton-gated cation channel ASIC1a.
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Dual actions of Psalmotoxin at ASIC1a and ASIC2a heteromeric channels (ASIC1a/2a).
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Modulating ion channels with nanobodies.
Synth Syst Biotechnol. 2025 Feb 18;10(2):593-599. doi: 10.1016/j.synbio.2025.02.005. eCollection 2025 Jun.
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Epithelial Na Channels Function as Extracellular Sensors.
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Nanobody engineering: computational modelling and design for biomedical and therapeutic applications.
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Photomodulation of the ASIC1a acidic pocket destabilizes the open state.
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AFTM: a database of transmembrane regions in the human proteome predicted by AlphaFold.
Database (Oxford). 2023 Mar 14;2023. doi: 10.1093/database/baad008.
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Nanobodies: Robust miniprotein binders in biomedicine.
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Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix.
Acta Crystallogr D Struct Biol. 2019 Oct 1;75(Pt 10):861-877. doi: 10.1107/S2059798319011471. Epub 2019 Oct 2.
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Software tools for automated transmission electron microscopy.
Nat Methods. 2019 Jun;16(6):471-477. doi: 10.1038/s41592-019-0396-9. Epub 2019 May 13.
7
Gating mechanisms of acid-sensing ion channels.
Nature. 2018 Mar 15;555(7696):397-401. doi: 10.1038/nature25782. Epub 2018 Mar 7.
9
A Strategy for Production of Correctly Folded Disulfide-Rich Peptides in the Periplasm of E. coli.
Methods Mol Biol. 2017;1586:155-180. doi: 10.1007/978-1-4939-6887-9_10.
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Acid-sensing ion channel (ASIC) structure and function: Insights from spider, snake and sea anemone venoms.
Neuropharmacology. 2017 Dec;127:173-184. doi: 10.1016/j.neuropharm.2017.04.042. Epub 2017 Apr 27.

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