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北美的蛇伤登记处报告的得克萨斯珊瑚蛇(Micrurus tener)咬伤的流行病学、临床特征和处理。

Epidemiology, Clinical Features, and Management of Texas Coral Snake (Micrurus tener) Envenomations Reported to the North American Snakebite Registry.

机构信息

Department of Emergency Medicine, Wright State University Boonshoft School of Medicine, Dayton, OH, USA.

Unviersity of Texas Health Science Center Cizik School of Nursing, 6711 Stella Link Rd, Houston, TX, 77005, USA.

出版信息

J Med Toxicol. 2021 Jan;17(1):51-56. doi: 10.1007/s13181-020-00806-3. Epub 2020 Aug 14.

Abstract

INTRODUCTION

Few of the 5000-8000 snakebites reported to poison control centers annually in the USA are attributed to coral snakes. This study describes Texas coral snake envenomations reported to the North American Snakebite Registry.

METHODS

All Texas coral snake envenomation cases reported to the registry were identified for the period from January 1, 2015, through December 31, 2019. Data reviewed for this study included details regarding the snake encounter, patient demographics, signs and symptoms, treatment, and outcomes. Descriptive statistics were used to report results.

RESULTS

Ten men and four nonpregnant women reported coral snake bites. The median patient age was 15.5 (range 5-72 years). There were 12 upper extremity bites and two bites to the lower extremity. The most common symptoms reported were paresthesias and pain. All subjects had paresthesias, often described as an "electric" sensation. Seven patients described them as painful. The most common clinical findings were erythema and swelling. No patient developed tissue damage, hematotoxicity, rhabdomyolysis, hypotension, weakness, or respiratory symptoms. Thirteen subjects were treated with opioids. Six patients were treated with antiemetics: three prophylactically and two for opioid-induced nausea. One patient developed nausea and non-bloody, nonbilious emesis within 1 hour of the bite, prior to receiving opioids. No patients were treated with antivenom. Antibiotics were not administered to any patient, and no infections were reported.

CONCLUSIONS

Envenomations from M. tener in Southeast Texas are characterized by painful paresthesias. Mild swelling and erythema are common. Neurotoxicity necessitating antivenom or mechanical ventilation did not occur.

摘要

简介

在美国,每年向中毒控制中心报告的 5000-8000 例蛇咬伤中,只有少数归因于珊瑚蛇。本研究描述了向北美蛇咬伤登记处报告的德克萨斯珊瑚蛇中毒事件。

方法

从 2015 年 1 月 1 日至 2019 年 12 月 31 日,确定向登记处报告的所有德克萨斯珊瑚蛇中毒病例。本研究审查的数据包括与蛇接触、患者人口统计学、体征和症状、治疗和结果有关的详细信息。使用描述性统计数据报告结果。

结果

10 名男性和 4 名非孕妇报告了珊瑚蛇咬伤。中位患者年龄为 15.5 岁(范围 5-72 岁)。有 12 例上肢咬伤和 2 例下肢咬伤。报告的最常见症状是感觉异常和疼痛。所有患者均有感觉异常,常描述为“电击”感。7 名患者描述为疼痛。最常见的临床发现是红斑和肿胀。没有患者出现组织损伤、血液毒性、横纹肌溶解、低血压、无力或呼吸症状。13 名患者接受了阿片类药物治疗。6 名患者接受了止吐药治疗:3 名预防性治疗,2 名用于阿片类药物引起的恶心。一名患者在咬伤后 1 小时内出现恶心和非血性、非胆汁性呕吐,此前未接受阿片类药物治疗。没有患者接受抗蛇毒血清治疗。没有给任何患者使用抗生素,也没有报告感染。

结论

在德克萨斯州东南部,M. tener 引起的中毒表现为疼痛性感觉异常。轻度肿胀和红斑很常见。不需要抗蛇毒血清或机械通气的神经毒性并未发生。

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