Children's Hospital Colorado and Department of Orthopedics, University of Colorado School of Medicine, Aurora (Dr Howell); Boston Children's Hospital, Boston, Massachusetts (Ms Hunt and Drs Oldham and Meehan); and Spaulding Rehabilitation Hospital, Cambridge, Massachusetts (Drs Aaron and Tan).
J Head Trauma Rehabil. 2022;37(4):249-257. doi: 10.1097/HTR.0000000000000718. Epub 2021 Jul 26.
To examine the association between postconcussion exercise volume and changes in depression, anxiety, dizziness, and postural stability.
Secondary analysis of a single-site prospective clinical trial.
Cerebrovascular research laboratory.
Participants completed questionnaires and underwent tests of gait and balance within 2 weeks of a concussion (mean = 11 ± 3 days postconcussion) and approximately 1 month later (mean = 41 ± 7 days postconcussion). Exercise volume was tracked by weekly exercise logs.
On the basis of a previous work classifying exercise volume following concussion, we grouped participants according to self-reported exercise volume between visits as high exercise volume (≥150 min/wk) or low exercise volume (<150 min/wk).
Participants completed assessments evaluating anxiety and depression (Hospital Anxiety and Depression Scale), dizziness (Dizziness Handicap Inventory), and postural stability (tandem gait and modified Balance Error Scoring System).
Thirty-eight participants completed the study, of which 22 were in the high exercise volume group (mean = 71 ± 40 min/wk; 16.8 ± 2.1 years; 59% female) and 16 were in the low exercise volume group (mean = 379 ± 187 min/wk; 17.5 ± 2.1 years; 31% female). Although depression symptoms were not significantly different initially (mean difference = 1.5; 95% CI, -0.68 to 3.68; P = .24), the high exercise volume group had significantly lower depression symptom scores at follow-up (mean difference = 3.0; 95% CI, 1.40 to 4.47; P < .001). Anxiety symptoms (mean difference = 2.8; 95% CI, 0.3 to 5.4; P = 0.03), dizziness symptoms (mean difference = 10.9; 95% CI, 0.2 to 21.5; P = .047), single-task tandem gait (mean difference = 3.1 seconds; 95% CI, 0.2 to 6.0; P = .04), and dual-task tandem gait (mean difference = 4.2 seconds; 95% CI, 0.2 to 8.2; P = .04) were significantly better among the high exercise volume group.
Greater exercise volumes were associated with lower depression, anxiety, and dizziness symptoms, and faster tandem gait performance. These preliminary findings suggest a potentially beneficial role for exercise within several different domains commonly affected by concussion.
研究脑震荡后运动量与抑郁、焦虑、头晕和姿势稳定性变化之间的关系。
单站点前瞻性临床试验的二次分析。
脑血管研究实验室。
参与者在脑震荡后 2 周内（平均 11 ± 3 天）和大约 1 个月后（平均 41 ± 7 天）完成了问卷调查和步态及平衡测试。运动强度通过每周运动记录进行跟踪。
根据之前对脑震荡后运动量的分类工作，我们根据两次就诊之间的自我报告运动量将参与者分为高运动量组（≥150 分钟/周）或低运动量组（<150 分钟/周）。
参与者完成了评估焦虑和抑郁的问卷（医院焦虑和抑郁量表）、头晕（头晕障碍量表）和姿势稳定性（双足步态和改良平衡错误评分系统）。
38 名参与者完成了研究，其中 22 名在高运动量组（平均 71 ± 40 分钟/周；年龄 16.8 ± 2.1 岁；59%为女性），16 名在低运动量组（平均 379 ± 187 分钟/周；年龄 17.5 ± 2.1 岁；31%为女性）。尽管抑郁症状最初没有显著差异（平均差异= 1.5；95%置信区间，-0.68 至 3.68；P=.24），但高运动量组在随访时的抑郁症状评分明显更低（平均差异= 3.0；95%置信区间，1.40 至 4.47；P<.001）。焦虑症状（平均差异= 2.8；95%置信区间，0.3 至 5.4；P=.03）、头晕症状（平均差异= 10.9；95%置信区间，0.2 至 21.5；P=.047）、单任务双足步态（平均差异= 3.1 秒；95%置信区间，0.2 至 6.0；P=.04）和双任务双足步态（平均差异= 4.2 秒；95%置信区间，0.2 至 8.2；P=.04）在高运动量组中明显更好。
更大的运动量与更低的抑郁、焦虑和头晕症状以及更快的双足步态表现相关。这些初步发现表明，运动在几个常见的脑震荡影响领域可能具有潜在的有益作用。
