Department of Graduate School, Qinghai University, Xining, China.
Department of neurosurgery, Qinghai Provincial People's Hospital, Xining, China.
Br J Neurosurg. 2023 Dec;37(6):1693-1698. doi: 10.1080/02688697.2021.1950635. Epub 2021 Jul 10.
Intracranial epidermoid cyst is a rare pseudotumor of the nervous system, accounting for 0.2%-1.8% of all intracranial tumors. It is usually located in the cerebellopontine Angle or parasellar area, with insipid onset, slow growth and usually less than 2 cm in diameter. Giant epidermoid cysts that invade the bone have rarely been reported in the literature. Herein, we report a case of giant ECs extradural to the parietal bone, penetrating the skull and continuing to expand outward. In addition, a systematic search of four authoritative databases was conducted to collect the relevant reports of giant epidermoid cyst with diameter > 5cm for the first time, and to discuss the clinical and radiographic features of patients with giant epidermoid cyst and the influence of treatment options.
颅内表皮样囊肿是一种罕见的神经系统假性肿瘤,占所有颅内肿瘤的 0.2% - 1.8%。它通常位于小脑脑桥角或鞍旁区,发病隐匿,生长缓慢,通常直径小于 2cm。文献中很少有报道巨大的表皮样囊肿侵犯骨骼。本文报告 1 例巨大的 ECs 位于顶骨外硬膜,穿透颅骨并继续向外扩张。此外,首次通过系统检索四个权威数据库,收集直径> 5cm 的巨大表皮样囊肿的相关报道,讨论巨大表皮样囊肿患者的临床和影像学特征及治疗方案选择的影响。