Peerakul Yuthasak, Leeyaphan Jirapong, Rojjananukulpong Karn
Bamrasnaradura Infectious Diseases Institute, Department of Disease Control, Ministry of Public health, 38 Talat Khwan, Mueang, Nonthaburi, 11000, Thailand.
Knee Surg Relat Res. 2021 Jul 28;33(1):22. doi: 10.1186/s43019-021-00107-1.
The prevalence of osteoporosis in patients who undergo a primary total knee arthroplasty (TKA) is increasing. Low bone mineral density (BMD) is related to unfavorable outcomes following TKA such as migration of uncemented tibial components. Postoperative blood loss in TKA is an important complication. Non-modifying predicting factors for postoperative blood loss in patients undergoing primary TKA need further elucidation. Studies on the association between BMD and blood loss after TKA are limited. We aimed to demonstrate the relationship between BMD and postoperative drainage volume following primary TKA.
A cross-sectional study was conducted between January 2014 and August 2020. A total of 119 primary varus osteoarthritis knees with BMD results were included in the study. Patients with secondary causes of osteoporosis were excluded.
The median postoperative drainage volume of participants in the normal total hip BMD group and the normal trochanter BMD group was higher than that of patients in the low total hip BMD group and the low trochanter BMD group (285.0 ml vs 230.0 ml, P = 0.003; 282.5 ml vs 240.0 ml, P = 0.013, respectively). Multivariate regression analyses showed that operative time, spinal anesthesia, and normal total hip BMD status were significant predictive factors associated with increased postoperative drainage volume (P = 0.014, 0.022, and 0.013, respectively). No association was identified between the lumbar spine BMD status and postoperative drainage volume.
The relationship between BMD and postoperative blood loss in primary TKA was identified in this study. Normal total hip BMD was found to be associated with an increased postoperative drainage volume after primary TKA compared with low BMD.
接受初次全膝关节置换术(TKA)的患者中骨质疏松症的患病率正在上升。低骨密度(BMD)与TKA术后不良结局相关,如非骨水泥固定胫骨部件的移位。TKA术后失血是一种重要的并发症。对于接受初次TKA的患者,术后失血的非修正预测因素需要进一步阐明。关于TKA后BMD与失血之间关联的研究有限。我们旨在证明初次TKA后BMD与术后引流量之间的关系。
在2**014年1月至2020年8月期间进行了一项横断面研究。共有119例有BMD结果的初次内翻性骨关节炎膝关节纳入研究。排除有继发性骨质疏松症病因的患者。
正常全髋BMD组和正常大转子BMD组参与者的术后中位引流量高于低全髋BMD组和低大转子BMD组患者(分别为285.0 ml对230.0 ml,P = 0.003;282.5 ml对240.0 ml,P = 0.013)。多因素回归分析显示,手术时间、脊髓麻醉和正常全髋BMD状态是与术后引流量增加相关的显著预测因素(分别为P = 0.014、0.022和0.013)。未发现腰椎BMD状态与术后引流量之间存在关联。
本研究确定了初次TKA中BMD与术后失血之间的关系。与低BMD相比,发现正常全髋BMD与初次TKA术后引流量增加有关。