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中国南方地区减重手术前营养状况的一项初步研究。

A Pilot Study of Nutritional Status Prior to Bariatric Surgery in South China.

作者信息

Sun Linli, Wang Chunxia, Sun Wei, Wang Chunjiang

机构信息

Department of General Surgery, The Third Xiangya Hospital, Central South University, Changsha, China.

Yinan County People's Hospital, Linyi, China.

出版信息

Front Nutr. 2021 Jul 12;8:697695. doi: 10.3389/fnut.2021.697695. eCollection 2021.

Abstract

The was a pilot study to assess the biochemical and historical information about bariatric patients before undergoing the surgery in the aim of identifying nutritional deficiencies and their prevalence from 2015 to 2020. Clinical data of 247 patients (105 males and 142 females) were included. Vitamins, trace elements, electrolytes, albumin, globulin, hemoglobin, folate, ferritin, microalbuminuria (MAU), and parathyroid hormone (PTH) levels were determined to explore the nutritional status according to gender, age, high body mass index (BMI), and waist circumstance (WC). The mean age, mean BMI, and mean WC of the candidates were 32.95 ± 10.46 years, 38.01 ± 7.11 kg/m, and 117.04 ± 16.18 cm, respectively. The prevalence of preoperative nutritional deficiencies was 76.88% for 25 (OH) vitamin D, 19.84% for globulin, 11.74% for albumin, 11.02% for sodium, 8.33% for folic acid, 10.48% (male) and 6.34% (female) for chloride, 4.05% for calcium, 3.07% (male) and 0.70%(female) for ferritin, 11.90% for elevated PTH, and 44.96% for MAU. Males exhibited increased prevalence of globulin and MAU relative to females ( < 0.05). Older groups are more likely to exhibit albumin deficiency ( = 0.007), globulin deficiency ( = 0.003), and zinc deficiency ( = 0.015). In addition, 25 (OH) D deficiency and albumin deficiency were more common in patients with BMI ≥ 47.5 kg/m ( = 0.049 and 0.015, respectively). Wider WC (≥150 cm) exhibited higher rates of albumin deficiencies ( = 0.011). Electrolyte and nutritional deficiencies were common in patients prior to bariatric surgery in South China. Routine evaluation of electrolyte and nutritional levels should be carried out in this population.

摘要

这是一项前瞻性研究,旨在评估肥胖症患者在接受手术前的生化和病史信息,以确定2015年至2020年期间营养缺乏情况及其患病率。纳入了247例患者(105例男性和142例女性)的临床数据。测定维生素、微量元素、电解质、白蛋白、球蛋白、血红蛋白、叶酸、铁蛋白、微量白蛋白尿(MAU)和甲状旁腺激素(PTH)水平,以根据性别、年龄、高体重指数(BMI)和腰围(WC)探索营养状况。候选者的平均年龄、平均BMI和平均WC分别为32.95±10.46岁、38.01±7.11kg/m²和117.04±16.18cm。术前营养缺乏的患病率分别为:25(OH)维生素D为76.88%,球蛋白为19.84%,白蛋白为11.74%,钠为11.02%,叶酸为8.33%,氯为10.48%(男性)和6.34%(女性),钙为4.05%,铁蛋白为3.07%(男性)和0.70%(女性),PTH升高为11.90%,MAU为44.96%。男性球蛋白和MAU的患病率相对于女性有所增加(P<0.05)。年龄较大的组更有可能出现白蛋白缺乏(P=0.007)、球蛋白缺乏(P=0.003)和锌缺乏(P=0.015)。此外,BMI≥47.5kg/m²的患者中25(OH)D缺乏和白蛋白缺乏更为常见(分别为P=0.049和0.015)。腰围较宽(≥150cm)的患者白蛋白缺乏率较高(P=0.011)。中国南方肥胖症手术患者术前电解质和营养缺乏情况较为常见。应对该人群进行电解质和营养水平的常规评估。

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