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急诊房颤病例量对新发房颤患者早期和晚期结局的影响。

Impact of Atrial Fibrillation Case Volume in the Emergency Department on Early and Late Outcomes of Patients With New Atrial Fibrillation.

机构信息

Centre for Cardiovascular Innovation, University of British Columbia, Vancouver, Canada.

Alberta SPOR Support Unit Data Platform, University of Alberta, Edmonton, Canada.

出版信息

Ann Emerg Med. 2021 Aug;78(2):242-252. doi: 10.1016/j.annemergmed.2021.03.014.

Abstract

STUDY OBJECTIVE

To define the association between atrial fibrillation case volume in the emergency department and death or all-cause hospitalization at 30 days and 1 year in patients with new atrial fibrillation. Secondary objectives examined repeat ED visits and the management of atrial fibrillation within 90 days.

METHODS

We identified all adults presenting to an ED in Alberta, Canada, with a new primary diagnosis of atrial fibrillation/flutter between 2009 and 2015 using International Classification of Diseases, 10th Revision code I48. Volume was classified in tertiles weighted by annual ED number of atrial fibrillation cases. The association between volume and outcomes was evaluated using generalized linear mixed models, adjusting for prognostically important covariates as fixed effects and ED as a random effect to account for potential clustering within EDs.

RESULTS

The tertiles consisted of 4 high, 9 medium, and 68 low atrial fibrillation volume EDs, with 4,217, 4,193, and 4,112 patients, respectively. Volume was not independently associated with the primary outcome or individual components. However, medium- and high-volume EDs had fewer repeat ED visits at 30 days (respective adjusted odds ratio [aOR] 0.75 [95% confidence interval {CI} 0.66 to 0.87] and 0.64 [0.52 to 0.79]) and 1 year (respective aOR 0.77 [95% CI 0.67 to 0.90] and 0.71 [0.56 to 0.90]). Fewer patients were admitted from medium- (37.1%) and high- (32.0%) compared with low-volume (39.5%) EDs. Patients attending medium- and high-volume EDs were more likely to be cardioverted (aOR 3.28 [95% CI 1.94 to 5.53] and 3.81 [1.39 to 10.48] for medium- and high-volume EDs, respectively).

CONCLUSION

Treatment in higher volume EDs was associated with significantly lower admission rates and repeat ED visits but no difference in survival.

摘要

研究目的

明确急诊科新发心房颤动患者的房颤病例量与 30 天和 1 年时死亡或全因住院的关系。次要目标为观察 90 天内再次急诊就诊和房颤管理情况。

方法

我们采用加拿大艾伯塔省 2009 年至 2015 年国际疾病分类第 10 版编码 I48 识别所有新诊断为心房颤动/心房扑动的成年急诊患者。根据房颤病例的年急诊就诊人数对病例量进行三分位加权分类。采用广义线性混合模型评估病例量与结局之间的关系,以固定效应调整预后重要的混杂因素,并将急诊就诊作为随机效应,以解释潜在的急诊就诊内聚类。

结果

三分位组分别包含 4 家高容量、9 家中容量和 68 家低容量的房颤急诊就诊医院,分别纳入 4217、4193 和 4112 例患者。病例量与主要结局或各组成部分均无独立相关性。然而,中容量和高容量的急诊就诊医院在 30 天时的再次急诊就诊率更低(校正比值比分别为 0.75 [95%置信区间 0.66 至 0.87] 和 0.64 [0.52 至 0.79]),1 年时更低(分别为 0.77 [95%置信区间 0.67 至 0.90] 和 0.71 [0.56 至 0.90])。与低容量的急诊就诊医院(39.5%)相比,中容量(37.1%)和高容量(32.0%)的急诊就诊医院收治的患者更少。接受中容量和高容量的急诊就诊医院治疗的患者更有可能接受电复律(校正比值比分别为 3.28 [95%置信区间 1.94 至 5.53] 和 3.81 [1.39 至 10.48])。

结论

在高容量的急诊就诊医院接受治疗与较低的收治率和再次急诊就诊率显著相关,但生存率无差异。

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