改良活动评估量表最小临床重要差异的验证。
Validation of the minimal clinically important difference for modified activities assessment scale.
机构信息
Department of Surgery, McGovern Medical School at UTHealth, Houston, TX, United States; Center for Surgical Trials and Evidence-Based Practice, McGovern Medical School at UTHealth, Houston, TX, United States.
Department of Surgery, McGovern Medical School at UTHealth, Houston, TX, United States; Center for Surgical Trials and Evidence-Based Practice, McGovern Medical School at UTHealth, Houston, TX, United States.
出版信息
Am J Surg. 2022 Apr;223(4):770-773. doi: 10.1016/j.amjsurg.2021.07.042. Epub 2021 Jul 24.
BACKGROUND
The minimal clinically important difference (MCID) is the smallest change in patient-derived scores that is clinically important. We sought to validate the MCID of the modified activities assessment scale (mAAS).
METHODS
Patients were surveyed prior to undergoing abdomen/pelvis CT scans and resurveyed one year later. Before resurvey, patients were asked if they had no change, worsening, or improvement in AW-QOL. The anchor-based MCID was calculated by taking a weighted mean of the difference between control (no change) and study (worsening/improved) groups. Distribution-based approach was calculated by one-half of the standard deviation in the QOL change.
RESULTS
52.8% of 181 patients self-reported no change, 39.2% reported improvement, and 8.3% reported worsening AW-QOL. The anchor-based approach MCID was 4. The distribution-based MCID was 16.
CONCLUSION
Our study results validate prior work demonstrating similar ranges of the mAAS MCID. We recommend adopting an MCID of 5 and 15 for AW-QOL with mAAS.
背景
最小临床重要差异（MCID）是指患者评分变化中最能体现临床重要性的最小变化。我们旨在验证改良活动评估量表（mAAS）的 MCID。
方法
患者在接受腹部/骨盆 CT 扫描前接受调查，并在一年后进行随访。在再次调查之前，患者被问到 AW-QOL 是否没有变化、恶化或改善。基于锚定的 MCID 通过取对照组（无变化）和研究组（恶化/改善）之间差异的加权平均值来计算。基于分布的方法通过 QOL 变化的标准差的一半来计算。
结果
181 名患者中有 52.8%报告 AW-QOL 无变化，39.2%报告改善，8.3%报告恶化。基于锚定的 MCID 为 4。基于分布的 MCID 为 16。
结论
我们的研究结果验证了先前的工作，表明 mAAS 的 MCID 范围相似。我们建议采用 mAAS 的 AW-QOL 的 MCID 为 5 和 15。
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