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系统评价和心理干预对冠心病患者的荟萃分析。

Systematic review and meta-analysis of psychological intervention on patients with coronary heart disease.

机构信息

Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Department of Nursing, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

出版信息

Ann Palliat Med. 2021 Aug;10(8):8848-8857. doi: 10.21037/apm-21-1623. Epub 2021 Jul 27.

DOI:10.21037/apm-21-1623
PMID:34328010
Abstract

BACKGROUND

Coronary heart disease is both a physical and mental disease, so psychological intervention can be used as part of a general cardiac rehabilitation plan. This study aimed to evaluate the effect of psychological intervention on the negative psychology of patients with coronary heart disease.

METHODS

Multiple databases like PubMed, Embase, Web of Science, and Cochrane Library were used to search for the relevant studies, and full-text articles involved in the evaluation of psychological intervention versus usual care for patients with coronary heart disease. Review Manager 5.4 (The Cochrane Collaboration, Software Update, Oxford, 2020) was adopted to estimate the effects of the results among selected articles. Forest plots, sensitivity analysis, and bias analysis were also performed on the included articles.

RESULTS

There were 17 studies that eventually met the final inclusion criteria. There were significant differences in anxiety level [mean difference (MD) -4.53; 95% confidence interval (CI), -6.36 to -2.7; P<0.00001; I2=96%], depression level (MD-3.43; 95% CI, -4.85 to -2.01; P<0.00001; I2=96%), and stress level (MD -4.19; 95% CI, -6.86 to -1.52; P<0.00001; I2=94%), but no difference was found for total mortality (P=0.50).

CONCLUSIONS

This study indicated that psychological intervention has important health benefits for patients with coronary heart disease and can effectively reduce negative psychological effects such as depression, anxiety, and stress. However, the results need to be further confirmed due to the limitations.

摘要

背景

冠心病既是一种身体疾病,也是一种心理疾病,因此心理干预可以作为心脏康复综合计划的一部分。本研究旨在评估心理干预对冠心病患者负面心理的影响。

方法

使用 PubMed、Embase、Web of Science 和 Cochrane Library 等多个数据库,检索评价心理干预与常规护理对冠心病患者影响的相关研究,纳入评价心理干预对比常规护理冠心病患者的全文文献。采用 Review Manager 5.4(The Cochrane Collaboration,Software Update,Oxford,2020)软件进行效应估计。对纳入文献进行森林图、敏感性分析和偏倚分析。

结果

最终有 17 项研究符合最终纳入标准。在焦虑水平[均数差(MD)-4.53;95%置信区间(CI),-6.36 至-2.7;P<0.00001;I2=96%]、抑郁水平(MD-3.43;95% CI,-4.85 至-2.01;P<0.00001;I2=96%)和应激水平(MD-4.19;95% CI,-6.86 至-1.52;P<0.00001;I2=94%)方面差异有统计学意义,但总死亡率方面差异无统计学意义(P=0.50)。

结论

本研究表明,心理干预对冠心病患者具有重要的健康益处,可有效降低抑郁、焦虑和应激等负面心理效应。但是,由于存在局限性,结果需要进一步证实。

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