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接受传统腹腔镜手术和经自然腔道内镜手术行卵巢囊肿切除术患者的隐匿性失血及其危险因素

Hidden blood loss and its risk factors in patients undergoing conventional laparoscopic surgery and laparoendoscopic single-site surgery for ovarian cystectomy.

作者信息

Chen Qiuyu, Zhu Sennan, Wang Danhan, Chen Miaomiao, Zhao Yu, Zhang Qiong

机构信息

Department of Gynecology and Obstetrics, The Second Affiliated Hospital and Yuying, Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

出版信息

Int J Gynaecol Obstet. 2022 May;157(2):424-430. doi: 10.1002/ijgo.13842. Epub 2021 Aug 19.

Abstract

OBJECTIVE

To quantify the volume of hidden blood loss (HBL) between conventional laparoscopic surgery (CLS) and laparoendoscopic single-site surgery (LESS) for ovarian cyst and to explore its risk factors.

METHODS

A total of 310 patients who underwent CLS or LESS were enrolled in this study. The Nadler formula and Gross formula were used to calculate each patient's estimated blood volume and total blood loss, multiple linear regression analysis was applied to identify the risk factors.

RESULTS

The HBL in LESS was more than in CLS (P = 0.000). Operative time (p = 0.015), pre-hematocrit (P = 0.002), pre-hemoglobin (P = 0.015), and pelvic adhesions (P = 0.037) were positively correlated with HBL in CLS. Intraoperative bleeding (P = 0.026), operative time (P = 0.000), pre-hematocrit (P = 0.042), CA125 (P = 0.047), and cyst volume (P = 0.012) were independent risk factors for HBL in LESS.

CONCLUSION

A large amount of HBL occurs in ovarian cystectomy surgery and cannot be ignored in clinical work; fully and correctly understanding HBL and exploring its causes can ensure the safety and improve the prognosis of patients.

摘要

目的

量化传统腹腔镜手术(CLS)与单孔腹腔镜手术(LESS)治疗卵巢囊肿时隐匿性失血(HBL)的量,并探讨其危险因素。

方法

本研究共纳入310例行CLS或LESS的患者。采用Nadler公式和Gross公式计算每位患者的估计血容量和总失血量,应用多元线性回归分析确定危险因素。

结果

LESS组的HBL多于CLS组(P = 0.000)。CLS组中,手术时间(P = 0.015)、术前血细胞比容(P = 0.002)、术前血红蛋白(P = 0.015)和盆腔粘连(P = 0.037)与HBL呈正相关。LESS组中,术中出血(P = 0.026)、手术时间(P = 0.000)、术前血细胞比容(P = 0.042)、CA125(P = 0.047)和囊肿体积(P = 0.012)是HBL的独立危险因素。

结论

卵巢囊肿切除术中存在大量HBL,临床工作中不容忽视;充分正确认识HBL并探究其原因可确保患者安全并改善预后。

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