Perić Aleksandar, Sotirović Jelena, Folić Miljan, Đurdević Biserka Vukomanović
Department of Otorhinolaryngology, Faculty of Medicine of the Military Medical Academy, University of Defence, Belgrade, Serbia.
Clinic for Otorhinolaryngology and Maxillofacial Surgery, University Clinical Centre of Serbia, Faculty of Medicine, University in Belgrade, Belgrade, Serbia.
Ear Nose Throat J. 2024 Jan;103(1):NP7-NP9. doi: 10.1177/01455613211036241. Epub 2021 Jul 30.
Angiomyolipoma is a benign, mesenchymal, hamartomatous lesion often described in the kidney and may be associated with tuberous sclerosis. Nasal angiomyolipoma is an extremely rare tumor with fewer than 20 cases reported in the literature. We report a case of angiomyolipoma arising in the right nasal vestibule in a 68-year-old male with mild, recurrent right-sided epistaxis, and nasal obstruction. With the exception of arterial hypertension, the patient did not have any comorbidities. Gross examination showed a well-circumscribed, lobulated mass. On the microscopic level, it was composed of mature smooth muscle cells, thick-walled blood vessels of varying sizes, and islands of mature adipose tissue. Angiomyolipoma should be considered as a differential diagnosis for unilateral nasal masses, especially those situated in the nasal vestibule.
血管平滑肌脂肪瘤是一种良性的间叶性错构瘤病变，常见于肾脏，可能与结节性硬化症有关。鼻血管平滑肌脂肪瘤是一种极其罕见的肿瘤，文献报道的病例少于20例。我们报告一例68岁男性右侧鼻前庭发生的血管平滑肌脂肪瘤，患者有轻度复发性右侧鼻出血和鼻塞。除动脉高血压外，患者无任何合并症。大体检查显示为边界清楚、分叶状肿块。显微镜下，它由成熟的平滑肌细胞、大小不一的厚壁血管和成熟脂肪组织岛组成。血管平滑肌脂肪瘤应被视为单侧鼻腔肿物的鉴别诊断之一，尤其是位于鼻前庭的肿物。
