Department of Burns and Plastic Surgery, The Children's Hospital of Chongqing Medical University, 136 Zhongshan Second Road, Yuzhong District, Chongqing, 400014, China.
Department of Orthopedics, The Children's Hospital of Chongqing Medical University, 136 Zhongshan Second Road, Yuzhong District, Chongqing, 400014, China.
Pediatr Surg Int. 2021 Oct;37(10):1323-1332. doi: 10.1007/s00383-021-04947-6. Epub 2021 Jul 30.
The aim of this study was to evaluate effectiveness and safety of resistance training (RT). Data were retrieved from Medline, EMBASE, PubMed, CINAHL and Cochrane Central Register of Controlled Trials (Central) databases from inception to April 2020. Quantitative studies on RT for muscle strength, lean body mass, cardiopulmonary function, metabolism, quality of life, and pain in burned children were included in this study. Twelve RCTs (379 patients) were identified. Meta-analysis showed RT significant increase in muscle strength [SMD = 2.18, 95% CI (0.79, 3.56), p = 0.002]. However, training showed no significant effect on muscle endurance [MD = 10.00, 95% CI (- 0.22, 20.22), p = 0.06]. Notably, training significantly increases total lean body mass [MD = 2.10, 95% CI (1.28, 2.92), p < 0.001]. In addition, training significantly increased leg lean body mass [MD = 2.10, 95% CI (1.28, 2.92), p < 0.001]. Moreover, training significantly increased VOpeak [MD = 5.83, 95% CI (3.52, 8.13), p < 0.001]. Meta-analysis showed that training significantly increases gait parameters, including stride length, step length, velocity and cadence. Furthermore, training significantly increased explosive capacity of lower limb muscles (p < 0.001). Meta-analysis of 6-min walking test results showed that training significantly improves walking speed (p = 0.0008). Notably, all studies showed unclear or high risk of bias; whereas, quality of the evidence was moderate or low. Analysis showed that RT significantly improves clinical outcomes. However, more high-quality, double-blind, randomized control trials should be performed to explore the effects of RT to ensure successful implementation in rehabilitation.
本研究旨在评估抗阻训练（RT）的有效性和安全性。数据来自 Medline、EMBASE、PubMed、CINAHL 和 Cochrane 对照试验中心注册库，检索时间截至 2020 年 4 月。本研究纳入了评估烧伤儿童肌肉力量、瘦体重、心肺功能、代谢、生活质量和疼痛的 RT 的定量研究。共确定了 12 项 RCT（379 名患者）。Meta 分析显示，RT 可显著增加肌肉力量[SMD=2.18，95%CI（0.79，3.56），p=0.002]。然而，训练对肌肉耐力无显著影响[MD=10.00，95%CI（-0.22，20.22），p=0.06]。值得注意的是，训练可显著增加总瘦体重[MD=2.10，95%CI（1.28，2.92），p<0.001]。此外，训练可显著增加下肢瘦体重[MD=2.10，95%CI（1.28，2.92），p<0.001]。此外，训练可显著增加峰值摄氧量[MD=5.83，95%CI（3.52，8.13），p<0.001]。Meta 分析显示，训练可显著增加步态参数，包括步长、步幅、速度和步频。此外，训练可显著增加下肢肌肉爆发力（p<0.001）。6 分钟步行试验结果的 Meta 分析显示，训练可显著提高步行速度（p=0.0008）。所有研究均显示存在偏倚风险不明确或高，而证据质量为中或低。分析表明，RT 可显著改善临床结局。然而，需要更多高质量、双盲、随机对照试验来探究 RT 的效果，以确保在康复中成功实施。
