Gittings Paul M, Grisbrook Tiffany L, Edgar Dale W, Wood Fiona M, Wand Benedict M, O'Connell Neil E
State Adult Burn Service, Fiona Stanley Hospital, Murdoch, Western Australia, Australia; Fiona Wood Foundation, Perth, Western Australia, Australia; School of Physiotherapy, The University of Notre Dame Australia, Fremantle, Western Australia, Australia.
Fiona Wood Foundation, Perth, Western Australia, Australia; School of Physiotherapy and Exercise Science, Curtin University, Bentley, Western Australia, Australia.
Burns. 2018 Jun;44(4):731-751. doi: 10.1016/j.burns.2017.08.009. Epub 2017 Oct 7.
BACKGROUND/AIM: Resistance training is beneficial for rehabilitation in many clinical conditions, though this has not been systematically reviewed in burns. The objective was to determine the effectiveness of resistance training on muscle strength, lean mass, function, quality of life and pain, in children and adults after burn injury.
Medline & EMBASE, PubMed, CINAHL and CENTRAL were searched from inception to October 2016. Studies were identified that implemented resistance training in rehabilitation. Data were combined and included in meta-analyses for muscle strength and lean mass. Otherwise, narrative analysis was completed. The quality of evidence for each outcome was summarised and rated using the GRADE framework.
Eleven studies matched our inclusion criteria. Primary analysis did not demonstrate significant improvements for increasing muscle strength (SMD 0.74, 95% CI -0.02 to 1.50, p=0.06). Sensitivity analysis to correct an apparent anomaly in published data suggested a positive effect (SMD 0.37, 95% CI 0.08-0.65, p=0.01). Psychological quality of life demonstrated benefit from training (MD=25.3, 95% CI 3.94-49.7). All studies were rated as having high risk of bias. The quality of the evidence was rated as low or very low.
Further research with robust methodology is recommended to assess the potential benefit suggested in this review.
背景/目的：抗阻训练对多种临床疾病的康复有益，不过在烧伤领域尚未得到系统综述。本研究的目的是确定抗阻训练对烧伤后儿童和成人肌肉力量、去脂体重、功能、生活质量及疼痛的有效性。
检索了自数据库建库至2016年10月的Medline & EMBASE、PubMed、CINAHL和CENTRAL数据库。纳入在康复过程中实施抗阻训练的研究。合并数据并纳入肌肉力量和去脂体重的荟萃分析。否则，进行叙述性分析。使用GRADE框架总结并评价各结局的证据质量。
11项研究符合纳入标准。初步分析未显示抗阻训练在增加肌肉力量方面有显著改善（标准化均数差0.74，95%可信区间-0.02至1.50，p = 0.06）。针对已发表数据中一个明显异常进行的敏感性分析显示有积极效果（标准化均数差0.37，95%可信区间0.08 - 0.65，p = 0.01）。心理生活质量显示从训练中受益（平均差=25.3，95%可信区间3.94 - 49.7）。所有研究均被评为存在高偏倚风险。证据质量被评为低或极低。
建议采用可靠方法进行进一步研究，以评估本综述中提示的潜在益处。
