[内脏恶性肿瘤的血液学表现]

[Hematological masks of malignant neoplasms of the internal organs].

作者信息

Baĭdurin S A, Shilova V N, Iungbliut A A, Lokhvitskaia L B, Zhakipova A T

出版信息

Ter Arkh. 1987;59(10):108-11.

Abstract

Hematological "masks" of malignant tumors of the internal organs are not infrequent in clinical practice. A total of 45 patients with malignant tumors of the internal organs (stomach-12, colon-9, liver-3, lungs-9, kidneys-6, pancreas-2, thyroid-2, bladder-1, prostate-1) were under observation. Hematological signs of bone marrow metastatic involvement were as follows: anemia (mainly hypochromic), leukemoid neutrophilic reaction, leukemoid reaction of myeloid type, erythrocytosis, thrombocytosis, plasmocyte bone marrow reaction. Early cancer diagnosis, especially in obscure peripheral blood changes, requires a complete all-round investigation of a patient including an analysis of clinico-anamnestic data, the use of radiographic and endoscopic methods, sternal puncture and trephine biopsy.

摘要

恶性肿瘤的血液学“伪装”在临床实践中并不少见。共有45例内脏恶性肿瘤患者（胃癌12例、结肠癌9例、肝癌3例、肺癌9例、肾癌6例、胰腺癌2例、甲状腺癌2例、膀胱癌1例、前列腺癌1例）接受观察。骨髓转移受累的血液学表现如下：贫血（主要为低色素性）、类白血病中性粒细胞反应、髓样类白血病反应、红细胞增多、血小板增多、浆细胞骨髓反应。早期癌症诊断，尤其是在外周血变化不明显时，需要对患者进行全面彻底的检查，包括临床病史资料分析、影像学和内镜检查方法的应用、胸骨穿刺和环钻活检。