并发早期食管癌和秀丽隐杆线虫感染：一例报告。
Comorbid early esophageal cancer and Gongylonema pulchrum infection: a case report.
机构信息
Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Yongan Road, Xicheng District, Beijing, 10050, China.
Beijing Tropical Medicine Research Institute, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
出版信息
BMC Gastroenterol. 2021 Jul 31;21(1):305. doi: 10.1186/s12876-021-01873-8.
BACKGROUND
Gongylonema pulchrum is a zoonotic parasite rarely found in humans. To date, there have been no reports on the carcinogenic properties of G. pulchrum, and there are few reports overall on the relationship between esophageal cancer and parasites.
CASE PRESENTATION
This report describes the first case of esophageal gongylonemiasis coexisting with early esophageal cancer. The patient had no high-risk factors for esophageal cancer, such as smoking, flushing after drinking, or tumor history. We speculate the existence of unknown links between esophageal cancer and parasitic infection in this patient.
DISCUSSION AND CONCLUSIONS
We report the first case of a human presenting both esophageal G. pulchrum infection and esophageal squamous cell carcinoma with the hope that it may provide evidence for a new hypothesis of tumorigenesis.
背景
美丽毛线虫是一种罕见的人体寄生性蠕虫，目前尚未有关于美丽毛线虫致癌性的报道，有关食管癌与寄生虫关系的报道也很少。
病例介绍
本报告描述了首例合并早期食管癌的食管毛线虫病。该患者无食管癌高危因素，如吸烟、饮酒后呕吐、肿瘤病史等。我们推测该患者食管癌与寄生虫感染之间存在未知的联系。
讨论和结论
我们报告首例人类同时存在食管美丽毛线虫感染和食管鳞状细胞癌，希望这能为肿瘤发生的新假说提供证据。
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