卷尾猴（Lemur macaco variegata；凯尔，1792年）体内的美丽筒线虫感染与食管鳞状细胞癌

Gongylonema pulchrum infection and esophageal squamous cell carcinoma in a vari (Lemur macaco variegata; Kehr 1792).

作者信息

Bleier T, Hetzel U, Bauer C, Behlert O, Burkhardt E

机构信息

Institut für Veterinaer-Pathologie, Justus-Liebig-Universitaet Giessen, Frankfurter Strasse 96, Germany.

出版信息

J Zoo Wildl Med. 2005 Jun;36(2):342-5. doi: 10.1638/04-011.1.

DOI:10.1638/04-011.1

PMID:17323583

Abstract

This report describes the morphologic and histologic features of a case of esophageal Gongylonema pulchrum infection and esophageal squamous cell carcinoma in a 17-yr-old, female vari (Lemur macaco variegates). The lemur had lived in a German zoo and had a clinical history of dyspnea, vomiting, and anorexia. At necropsy, a whitish, soft, nodular, centrally necrotic mass was found in the caudal third of the esophagus. In addition, numerous intraepithelial nematodes (G. pulchrum) were observed in the entire esophagus. Results suggest a relation between infection with G. pulchrum and development of an esophageal squamous cell carcinoma.

摘要

本报告描述了一只17岁雌性黑白领狐猴（Lemur macaco variegates）食管美丽筒线虫感染及食管鳞状细胞癌的形态学和组织学特征。这只狐猴生活在德国一家动物园，有呼吸困难、呕吐和厌食的临床病史。尸检时，在食管尾段三分之一处发现一个白色、柔软、结节状、中央坏死的肿块。此外，在整个食管中观察到大量上皮内线虫（美丽筒线虫）。结果表明美丽筒线虫感染与食管鳞状细胞癌的发生之间存在关联。