Centre d'Etude et de Traitement de la Douleur, hôpital Pellegrin, CHU de Bordeaux, place Amélie Raba Léon, 33076 Bordeaux cedex, France.
Université Clermont Auvergne, Inserm U-1107, Neuro-Dol, 63000 Clermont-Ferrand, France.
Rev Neurol (Paris). 2021 Sep;177(7):760-764. doi: 10.1016/j.neurol.2021.07.003. Epub 2021 Jul 28.
Regular and frequent use of analgesics and acute antimigraine drugs can increase the frequency of headache, and induce the transition from episodic to chronic migraine or medication-overuse headache (MOH). The one-year prevalence of this condition is between 1% and 2% in Europe, provoking substantial burden. MOH is more prevalent in people with comorbid depression, anxiety, and other chronic pain conditions. This paper aims at presenting an updating of French recommendations regarding treatments strategies. Prior French recommendations, published in 2014, were written in French. A literature search in the major medical databases including the terms "medication overuse headache", "symptomatic medication overuse", published between 2010 and 2020 was carried out. Three main strategies can be recommended and conducted in parallel: education and explanations about the negative consequences of overusing acute antimigraine drugs, discontinuation of the overused medication, and finally, preventive drug therapy and non-pharmacological prevention. Medication overuse headache remains a debated problem and evidence for the most effective treatment strategy is needed.
经常使用镇痛药和急性偏头痛药物会增加头痛的频率，并导致发作性偏头痛向慢性偏头痛或药物过度使用性头痛（MOH）转化。这种情况在欧洲的一年患病率为 1%至 2%，带来了巨大的负担。MOH 在合并抑郁、焦虑和其他慢性疼痛疾病的人群中更为常见。本文旨在介绍法国关于治疗策略的最新建议。2014 年发表的先前法国建议是用法语书写的。在主要医学数据库中进行了一次文献检索，包括 2010 年至 2020 年期间发表的“药物过度使用性头痛”、“症状性药物过度使用”等术语。可以推荐并同时实施三种主要策略：关于过度使用急性偏头痛药物的负面后果的教育和解释、停止使用过度使用的药物，以及最后，预防性药物治疗和非药物预防。药物过度使用性头痛仍然是一个有争议的问题，需要有最有效的治疗策略的证据。
