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三维重建在复杂原发性肝癌精准肝切除术前评估中的应用价值

[Application value of three-dimensional reconstruction in preoperative evaluation of precise hepatectomy for complex primary liver cancer].

作者信息

Luo X, Li T, Zhu J Y, Huang L

机构信息

Department of Hepatobiliary Surgery, Peking University People's Hospital, Beijing 100044, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2021 Jul 27;101(28):2210-2215. doi: 10.3760/cma.j.cn112137-20210303-00548.

Abstract

To explore the application value of three-dimensional reconstruction of liver based on computer software in preoperative evaluation of precise hepatectomy for complex primary liver cancer. The clinical data of patients in Peking University People's Hospital Hepatobiliary surgery with complicated primary liver cancer from September 17, 2019 to December 20, 2020 were analyzed retrospectively. Preoperative enhanced CT/MR data of patients were collected, and 3D reconstruction of liver was performed in IQQA􀳏-3D Liver system. The liver volume of patients was calculated, the size and location of tumor were described, and the relationship between tumor and intrahepatic bile duct, portal vein, hepatic artery and inferior vena cava was described. Preoperative decision-making and treatment plan were made to compare the compliance of the actual operation plan with the planned operation plan under the guidance of three-dimensional reconstruction. Among all 10 patients, there were 6 males and 4 females, aged 36 to 75 years. There were 6 cases of Child-Pugh grade A and 4 cases of B liver function. There were 5 cases of portal vein variation and 5 cases of hepatic artery variation. The range and (,)of actual liver volume measured by 3D reconstruction in 10 patients was 895- 2 477 cm and [1 444(1 001, 1 854)] cm;the nodule volume was 7-1 808 [133(50, 566)] cm;the nodule volume in the liver was 0.8%-73.0% [11.0(3.3,32.7)]% and the number of suspected lesions was 1-7. In the end, 6 patients received surgical treatment;3 received chemotherapy, and 1 received conservative treatment. The preoperative three-dimensional reconstruction of liver anatomy and tumor location of the patients receiving surgical treatment were basically consistent with the intraoperative situation. There was no case of liver failure or death during perioperative period. In the preoperative evaluation of precise hepatectomy for complex primary liver cancer, 3D reconstruction can improve the rationality of treatment and the surgeon's understanding of the anatomical characteristics of the liver, so as to select the best treatment for patients, which has great application value.

摘要

探讨基于计算机软件的肝脏三维重建在复杂原发性肝癌精准肝切除术前评估中的应用价值。回顾性分析2019年9月17日至2020年12月20日北京大学人民医院肝胆外科收治的复杂原发性肝癌患者的临床资料。收集患者术前增强CT/MR数据,在IQQA􀳏-3D肝脏系统中进行肝脏三维重建。计算患者肝脏体积,描述肿瘤大小及位置,阐述肿瘤与肝内胆管、门静脉、肝动脉及下腔静脉的关系。制定术前决策及治疗方案,比较在三维重建指导下实际手术方案与计划手术方案的符合情况。10例患者中,男性6例,女性4例,年龄36~75岁。肝功能Child-Pugh A级6例,B级4例。门静脉变异5例,肝动脉变异5例。10例患者经三维重建测量的实际肝脏体积范围为895~2 477 cm,[1 444(1 001, 1 854)] cm;结节体积为7~1 808 [133(50, 566)] cm;肝脏内结节体积占比为0.8%~73.0% [11.0(3.3,32.7)]%,可疑病灶数为1~7个。最终,6例患者接受手术治疗;3例接受化疗,1例接受保守治疗。接受手术治疗患者的术前肝脏解剖及肿瘤位置三维重建与术中情况基本相符。围手术期无肝衰竭及死亡病例。在复杂原发性肝癌精准肝切除术前评估中,三维重建可提高治疗合理性及外科医生对肝脏解剖特征的认识,从而为患者选择最佳治疗方案,具有重要应用价值。

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