Orlins Zachary, Barnett Brian
Department of Psychiatry and Psychology, Center for Behavioral Health, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA.
Case Rep Psychiatry. 2021 Jul 16;2021:9954991. doi: 10.1155/2021/9954991. eCollection 2021.
Here, we present the case of a patient who initiated risperidone and developed persistent tachycardia, which was exacerbated by subsequent administration of paliperidone palmitate despite treatment with propranolol. This patient's experience emphasizes the need for psychiatrists to regularly monitor vital signs after risperidone/paliperidone initiation, dosage increase, or overdose to identify and appropriately manage this potentially harmful side effect. Increasing clinician awareness of this rare side effect will help protect patients with serious mental illness who regularly rely upon these medications, particularly in their long-acting injectable formulations.
在此，我们报告一例患者，该患者开始使用利培酮后出现持续性心动过速，尽管使用了普萘洛尔治疗，但后续使用棕榈酸帕利哌酮后心动过速加剧。该患者的经历强调，精神科医生在开始使用利培酮/帕利哌酮、增加剂量或过量用药后，需要定期监测生命体征，以识别并妥善处理这种潜在的有害副作用。提高临床医生对这种罕见副作用的认识，将有助于保护经常依赖这些药物（尤其是长效注射剂型）的严重精神疾病患者。
