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新鲜肱骨头骨软骨异体移植的采集、运输与储存:分步方案

Harvest, Transport, and Storage of Fresh Humeral Head Osteochondral Allograft: Step-by-Step Protocol.

作者信息

Borges Petros Rodrigo Souto, Prinz Rafael Augusto Dantas, Pinho Rodarte Rodrigo Ribeiro, Aguiar Diego Pinheiro, Branco de Sousa Eduardo

机构信息

Divisão de Ensino e Pesquisa, Instituto Nacional de Traumatologia e Ortopedia Jamil Haddad, São Cristóvão, Brazil.

Divisão de Banco Multitecidos, Instituto Nacional de Traumatologia e Ortopedia Jamil Haddad, São Cristóvão, Brazil.

出版信息

Arthrosc Tech. 2021 Jun 20;10(7):e1805-e1813. doi: 10.1016/j.eats.2021.03.025. eCollection 2021 Jul.

DOI:10.1016/j.eats.2021.03.025
PMID:34336579
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8322626/
Abstract

Articular cartilage defects are not common in the glenohumeral joint and are mostly found in patients after shoulder trauma, in patients with recurrent instability, or in patients who underwent previous surgical treatment. Articular cartilage defects lead to pain and loss of motion, consequently causing shoulder function impairment and reducing quality of life. In young patients, the use of osteochondral allografts for the treatment of humeral head defects may avoid well-known complications of shoulder arthroplasty. The goal of this Technical Note is to describe a step-by-step protocol for the harvesting, transport, and preservation of fresh humeral head osteochondral tissue for use in allograft transplantation.

摘要

关节软骨缺损在盂肱关节并不常见,大多见于肩部创伤后的患者、复发性不稳定患者或既往接受过手术治疗的患者。关节软骨缺损会导致疼痛和活动受限,进而造成肩部功能障碍并降低生活质量。对于年轻患者,使用同种异体骨软骨移植治疗肱骨头缺损可避免肩关节置换术的一些众所周知的并发症。本技术说明的目的是描述用于异体移植的新鲜肱骨头骨软骨组织的采集、运输和保存的分步方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff8/8322626/00515030c7fc/gr10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff8/8322626/47c897315466/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff8/8322626/9b5e100fe60b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff8/8322626/1965e67e561f/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff8/8322626/6f5f32f95d03/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff8/8322626/4c82f2f4e695/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff8/8322626/454bd1736bed/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff8/8322626/1798c2e6585e/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff8/8322626/eb89e47a8fb0/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff8/8322626/e29306c0d768/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff8/8322626/00515030c7fc/gr10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff8/8322626/47c897315466/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff8/8322626/9b5e100fe60b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff8/8322626/1965e67e561f/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff8/8322626/6f5f32f95d03/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff8/8322626/4c82f2f4e695/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff8/8322626/454bd1736bed/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff8/8322626/1798c2e6585e/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff8/8322626/eb89e47a8fb0/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff8/8322626/e29306c0d768/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ff8/8322626/00515030c7fc/gr10.jpg

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本文引用的文献

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J Am Acad Orthop Surg. 2020 Nov 15;28(22):914-922. doi: 10.5435/JAAOS-D-20-00266.
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Clinical Application of the Basic Science of Articular Cartilage Pathology and Treatment.关节软骨病理学与治疗的基础科学的临床应用。
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Protocol for Harvest, Transport and Storage of Human Osteochondral Tissue.人骨软骨组织采集、运输及储存方案
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Use of Allografts in Orthopaedic Surgery: Safety, Procurement, Storage, and Outcomes.同种异体移植物在骨科手术中的应用:安全性、获取、储存及结果
Orthop J Sports Med. 2019 Dec 30;7(12):2325967119891435. doi: 10.1177/2325967119891435. eCollection 2019 Dec.
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Evolution of a Novel Tissue Preservation Protocol to Optimize Osteochondral Transplantation Outcomes.新型组织保存方案的演进以优化软骨-骨复合体移植的效果。
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Management of Articular Cartilage Defects in the Glenohumeral Joint.肩关节软骨缺损的处理。
J Am Acad Orthop Surg. 2018 Jun 1;26(11):e230-e237. doi: 10.5435/JAAOS-D-17-00057.
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Arthrosc Tech. 2017 Aug 28;6(4):e1443-e1449. doi: 10.1016/j.eats.2017.06.008. eCollection 2017 Aug.
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