Casu Sebastian
Department of Emergency Medicine, Asklepios Hospital Wandsbek, Hamburg, Germany.
Trauma Surg Acute Care Open. 2021 Jul 16;6(1):e000779. doi: 10.1136/tsaco-2021-000779. eCollection 2021.
Uncontrolled bleeding after major trauma remains a significant cause of death, with up to a third of trauma patients presenting with signs of coagulopathy at hospital admission. Rapid correction of coagulopathy is therefore vital to improve mortality rates and patient outcomes in this population. Early and repeated monitoring of coagulation parameters followed by clear protocols to correct hemostasis is the recommended standard of care for bleeding trauma patients. However, although a number of treatment algorithms are available, these are frequently complex and can rely on the use of viscoelastic testing, which is not available in all treatment centers. We therefore set out to develop a concise and pragmatic algorithm to guide treatment of bleeding trauma patients without the use of point-of-care viscoelastic testing. The algorithm we present here is based on published guidelines and research, includes recommendations regarding treatment and dosing, and is simple and clear enough for even an inexperienced physician to follow. In this way, we have demonstrated that treatment protocols can be developed and adapted to the resources available, to offer clear and relevant guidance to the entire trauma team.
严重创伤后无法控制的出血仍然是一个重要的死亡原因,多达三分之一的创伤患者在入院时出现凝血功能障碍的迹象。因此,迅速纠正凝血功能障碍对于提高该人群的死亡率和患者预后至关重要。对于出血性创伤患者,建议的标准治疗方案是早期并反复监测凝血参数,随后按照明确的方案纠正止血。然而,尽管有多种治疗算法可供使用,但这些算法通常很复杂,且可能依赖于黏弹性检测,而并非所有治疗中心都具备这种检测手段。因此,我们着手开发一种简洁实用的算法,以指导出血性创伤患者的治疗,且无需使用即时黏弹性检测。我们在此展示的算法基于已发表的指南和研究,包括有关治疗和剂量的建议,甚至对于经验不足的医生来说也足够简单明了,便于遵循。通过这种方式,我们证明了可以制定并调整治疗方案以适应可用资源情况,从而为整个创伤团队提供清晰且相关的指导。