Peng Gary, Lin Aung N, Obeng-Gyimah Edmond, Hall Samantha N, Yang Ya-Wen, Chen Shiquan, Riley Michael, Deo Rajat, Ali Aasima, Arkles Jeffery, Epstein Andrew E, Dixit Sanjay
Electrophysiology Section, Division of Cardiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
Corporal Michael J. Crescenz Veteran Affairs Medical Center, Philadelphia, Pennsylvania.
Heart Rhythm O2. 2021 Apr 28;2(3):255-261. doi: 10.1016/j.hroo.2021.04.003. eCollection 2021 Jun.
Patients with typical atrial flutter (AFL) undergoing successful cavotricuspid isthmus ablation remain at risk for future development of new-onset atrial fibrillation (AF). Conventional monitoring (CM) techniques have shown AF incidence rates of 18%-50% in these patients.
To evaluate whether continuous monitoring using implantable loop recorders (ILRs) would enhance AF detection in this patient population.
Veteran patients undergoing AFL ablation between 2002 and 2019 who completed at least 6 months of follow-up after the ablation procedure were included. We compared new-onset AF detection between those who underwent CM and those who received ILRs immediately following AFL ablation.
A total of 217 patients (age: 66 ± 9 years; all male) participated. CM was used in 172 (79%) and ILR in 45 (21%) patients. Median follow-up duration after ablation was 4.1 years. Seventy-nine patients (36%) developed new-onset AF, which was detected by CM in 51 and ILR in 28 (30% vs 62%, respectively, < .001). AF detection occurred at 7.7 months (IQR: 4.7-17.5) after AFL ablation in the ILR group vs 41 months (IQR: 23-72) in the CM group ( < .001). Eleven patients (5%) experienced cerebrovascular events (all in the CM group) and only 4 of these patients (36%) were on long-term anticoagulation.
Patients undergoing AFL ablation remain at an increased risk of developing new-onset AF, which is detected sooner and more frequently by ILR than by CM. Improving AF detection may allow optimization of rhythm management strategies and anticoagulation in this patient population.
成功进行三尖瓣峡部消融的典型心房扑动(AFL)患者仍有新发心房颤动(AF)的风险。传统监测(CM)技术显示这些患者的AF发生率为18%-50%。
评估使用植入式环路记录仪(ILR)进行连续监测是否会提高该患者群体中AF的检出率。
纳入2002年至2019年间接受AFL消融且消融术后至少完成6个月随访的老年患者。我们比较了AFL消融后接受CM监测的患者和接受ILR监测的患者中新发AF的检出情况。
共有217例患者(年龄:66±9岁;均为男性)参与。172例(79%)患者使用CM,45例(21%)患者使用ILR。消融术后的中位随访时间为4.1年。79例(36%)患者发生新发AF,CM检测到51例,ILR检测到28例(分别为30%和62%,P<0.001)。ILR组在AFL消融后7.7个月(四分位间距:4.7-17.5)检测到AF,而CM组为41个月(四分位间距:23-72)(P<0.001)。11例(5%)患者发生脑血管事件(均在CM组),其中只有4例(36%)患者接受长期抗凝治疗。
接受AFL消融的患者发生新发AF的风险仍然增加,ILR比CM能更早、更频繁地检测到AF。改善AF检测可能有助于优化该患者群体的节律管理策略和抗凝治疗。