Musat Dan L, Milstein Nicolle S, Pimienta Jacqueline, Bhatt Advay, Preminger Mark W, Sichrovsky Tina C, Flynn Laura, Pistilli Carissa, Shaw Richard E, Mittal Suneet
Snyder Center for Comprehensive Atrial Fibrillation, Department of Cardiovascular Services, Valley Health System, Paramus, New Jersey.
Cardiovasc Digit Health J. 2020 Oct 29;1(3):114-122. doi: 10.1016/j.cvdhj.2020.10.003. eCollection 2020 Nov-Dec.
Following cavotricuspid isthmus (CTI) ablation, many patients with atrial flutter (AFL) are diagnosed with atrial fibrillation (AF). The incidence, duration, pattern, and burden of AF remain undefined. These may have implications for the management of these patients.
To classify the incidence, duration, pattern, and burden of AF/AFL using an implantable loop recorder (ILR) after CTI ablation.
We enrolled consecutive patients with CTI-dependent AFL, no known history of AF, and CHADS-VASc ≥ 2. An ILR was implanted before or within 90 days of ablation. The time to first AF/AFL, pattern, duration, and burden of longest AF/AFL were determined. Five distinct AF/AFL cohorts were identified: no AF/AFL and those with recurrences of isolated, clustered, frequent, or persistent AF/AFL.
Fifty-two patients (81% male; 73 ± 9 years; CHADS-VASc 3.7 ± 1.2) were followed for 784 (interquartile range [IQR] 263, 1150) days. AF/AFL occurred in 44 (85%) patients at 64 (IQR 8, 189) days post-CTI ablation and was paroxysmal in 31 (70%) patients (burden 0.6% [IQR 0.1, 4.8]). AF/AFL was isolated (n = 5, 11%), clustered (n =7, 16%), frequent (n =19, 43%), and persistent (n =13, 30%). The longest AF episode was <24 hours in 27 (61%) patients.
Following CTI ablation in AFL patients, although AF/AFL occurs in most patients, the burden is low and episodes were <24 hours in the majority of patients. Additional studies are needed to determine whether long-term electrocardiographic monitoring can help guide management of patients undergoing CTI ablation.
在三尖瓣峡部(CTI)消融术后,许多心房扑动(AFL)患者被诊断为心房颤动(AF)。AF的发生率、持续时间、类型及负荷仍不明确。这些情况可能对这些患者的管理有影响。
使用植入式环路记录仪(ILR)对CTI消融术后AF/AFL的发生率、持续时间、类型及负荷进行分类。
我们纳入了连续的CTI依赖型AFL患者,这些患者无已知AF病史且CHADS-VASc≥2。在消融术前或消融术90天内植入ILR。确定首次发生AF/AFL的时间、类型、持续时间以及最长AF/AFL的负荷。识别出五个不同的AF/AFL队列:无AF/AFL以及孤立性、成簇性、频发或持续性AF/AFL复发的患者。
52例患者(81%为男性;73±9岁;CHADS-VASc 3.7±1.2)随访了784(四分位间距[IQR]263,1150)天。44例(85%)患者在CTI消融术后64(IQR 8,189)天发生AF/AFL,其中31例(70%)患者为阵发性(负荷0.6%[IQR 0.1,4.8])。AF/AFL为孤立性(n = 5,11%)、成簇性(n = 7,16%)、频发(n = 19,43%)和持续性(n = 13,30%)。27例(61%)患者最长的AF发作<24小时。
在AFL患者进行CTI消融术后,虽然大多数患者会发生AF/AFL,但负荷较低且大多数患者发作时间<24小时。需要进一步研究以确定长期心电图监测是否有助于指导接受CTI消融术患者的管理。