Angle Orthod. 2022 Jan 1;92(1):127-136. doi: 10.2319/020721-111.1.
To provide collective quantitative evidence about the effect of surface treatments on the mechanical stability of orthodontic miniscrews (MSs).
The study was registered in PROSPERO (No. CRD42020209652). The research question was defined according to the PICO (population, intervention, control, and outcomes) format. Various research databases were searched for animal and human studies on effects of surface treatment on the mechanical stability of MSs. Both prospective and retrospective in vivo clinical studies published in English were included. The risk of bias was assessed using SYRCLE's risk of bias tool for animal studies. The meta-analysis was conducted using RevMan 5.4.
A total of 109 articles were identified; 14 were included in the systematic review, and seven studies with sandblasting, acid etching (SLA) methods of surface treatment were included for meta-analysis. The number of study participants ranged from 6 to 24 (total n = 185), with a mean of 13.2. A total of 949 MSs were used with a mean of 67.8. The overall success rate for surface-treated MSs ranged from 47.9% to 100%. Forest plot of removal torque values showed significantly higher values for SLA surface-treated MSs compared with controls with a standard mean difference of 2.61 (95% confidence interval = 1.49-3.72, I2 = 85%). Forest plot of insertion torque showed a standard mean difference of -6.19 (95% confidence interval = -13.63-1.25, I2 = 98%, P = .10).
Surface treatment of MSs improved primary and secondary stability with good osseointegration at the bone-implant surface. However, significant heterogeneity across the studies included in the meta-analysis made it difficult to draw conclusions.
提供有关表面处理对正畸微螺钉（MS）机械稳定性影响的集体定量证据。
该研究已在 PROSPERO（编号：CRD42020209652）中注册。根据 PICO（人群、干预、对照和结局）格式定义研究问题。搜索了各种研究数据库，以获取有关表面处理对 MS 机械稳定性影响的动物和人体研究。纳入了以英语发表的前瞻性和回顾性体内临床研究。使用 SYRCLE 的动物研究偏倚风险工具评估偏倚风险。使用 RevMan 5.4 进行荟萃分析。
共确定了 109 篇文章，其中 14 篇被纳入系统评价，7 篇采用喷砂酸蚀（SLA）表面处理方法的研究被纳入荟萃分析。研究参与者的数量从 6 到 24 人不等（总 n = 185），平均为 13.2 人。共使用了 949 颗 MS，平均每颗 67.8 颗。经表面处理的 MS 的总体成功率范围为 47.9%至 100%。去除扭矩值的森林图显示，SLA 表面处理的 MS 与对照组相比，去除扭矩值显著更高，标准均数差为 2.61（95%置信区间：1.49-3.72，I2 = 85%）。插入扭矩的森林图显示标准均数差为-6.19（95%置信区间：-13.63-1.25，I2 = 98%，P =.10）。
MS 的表面处理改善了初级和次级稳定性，并在骨-植入物表面实现了良好的骨整合。然而，荟萃分析中纳入的研究存在很大的异质性，使得难以得出结论。
