[Problems of the amino acid content in the blood plasma and their absorption in the intestines in chronic lead poisoning].

As against controls essential differences in the amino acids content were disclosed largely in patients with a well-marked form of poisoning, i. e. a fall in the level of 7 from among 17 amino acid under examination (valine, glycine, leucine, lysine, serine, tyrosine, phenylalanine). After a peroral administration of 100 gm of an amino acids mixture the increment in the amount of amino acids in the blood of these patients proved lower than in controls both after a lapse of 30 and 60 minutes. In patients with a mild form of poisoning a fall of the serine, tyrosine and phenylalanine level in the blood was ascertained. The amino acids loading revealed a lesser accretion of amino acids in the blood on expiration of 60 minutes. The specific D-penicillinamine medication had no effect on the amino acids content in the plasma and their absorption in the intestines.