Connolly B, Guiney E J, Fitzgerald R J
Children's Research Centre, Our Lady's Hospital for Sick Children, Crumlin, Dublin, Ireland, U.K.
Z Kinderchir. 1987 Dec;42 Suppl 1:13-4.
Thirty one patients were treated for 43 laboratory proven shunt or CSF infections, between 1980 to 1986 inclusive. They required 63 separate treatments. Infective episodes were grouped retrospectively according to method of treatment employed i.e. 1) placement of external drainage system or 2) reservoir and tapping, 3) intravenous or intraventricular antibiotics alone, 4) total change of shunt prosthesis, 5) partial change of prosthesis or 6) removal of all the prosthesis. See Table II. The single most important factor in eradication of shunt infection was the entire removal of the total shunt system and achieved success in 80% of instances. Conversely utilization of any of the existing infected system failed in 77% of cases. Route of administration of antibiotics, choice or change of side, or method of treatment chosen did not appear to influence success greatly.
1980年至1986年(含)期间,31名患者因43次经实验室证实的分流或脑脊液感染接受治疗。他们共需要63次单独治疗。感染发作根据所采用的治疗方法进行回顾性分组,即:1)放置外部引流系统;2)储液器及穿刺;3)单独静脉或脑室内使用抗生素;4)完全更换分流假体;5)部分更换假体;6)移除所有假体。见表二。根除分流感染的最重要因素是完全移除整个分流系统,80%的病例取得成功。相反,使用任何现有的感染系统,77%的病例治疗失败。抗生素的给药途径、部位的选择或更换,或所选的治疗方法似乎对成功率影响不大。