Mechanical Engineering Department, K.N. Toosi University of Technology, Tehran, Iran.
J Acoust Soc Am. 2021 Jul;150(1):233. doi: 10.1121/10.0005519.
The advantage of ultrasonic fields in harmless and label-free applications intrigued researchers to develop this technology. The capability of acoustofluidic technology for medical applications has not been thoroughly analyzed and visualized. Toward efficient design, in this research, flowing fluid in a microchannel excited by acoustic waves is fully investigated. To study the behavior of acoustic streaming, the main interfering parameters such as inlet velocity, working frequency, displacement amplitude, fluid buffer material, and hybrid effect in a rectangular water-filled microchannel actuated by standing surface acoustic waves are studied. Governing equations for acoustic field and laminar flow are derived employing perturbation theory. For each set of equations, appropriate boundary conditions are applied. Results demonstrate a parallel device is capable of increasing the inlet flow for rapid operations. Frequency increment raises the acoustic streaming velocity magnitude. Displacement amplitude amplification increases the acoustic streaming velocity and helps the streaming flow dominate over the incoming flow. The qualitative analysis of the hybrid effect shows using hard walls can significantly increase the streaming power without depleting excessive energy. A combination of several effective parameters provides an energy-efficient and fully controllable device for biomedical applications such as fluid mixing and cell lysis.
超声场在无害和无标记应用方面的优势引起了研究人员的兴趣，促使他们开发这项技术。声流控技术在医学应用方面的能力尚未得到彻底分析和可视化。为了实现高效设计，本研究全面研究了在声波激励下微通道中流动的流体。为了研究声流的行为，研究了主要干扰参数，如入口速度、工作频率、位移幅值、流体缓冲材料以及由驻波表面声波激励的矩形充水微通道中的混合效应。采用微扰理论推导出了声场和层流的控制方程。对于每组方程，都应用了适当的边界条件。结果表明，平行装置能够增加入口流量以实现快速操作。频率增加会提高声流速度。位移幅值放大会增加声流速度，并有助于声流主导入口流。混合效应的定性分析表明，使用硬壁可以显著增加流功率，而不会耗尽过多的能量。几个有效参数的组合为生物医学应用提供了一种节能且完全可控的设备，例如流体混合和细胞裂解。
