Ophthalmology, National University of Colombia, Bogotá, Colombia.
Department of Corneal, National University of Colombia, Bogotá, Colombia.
Arch Soc Esp Oftalmol (Engl Ed). 2021 Aug;96(8):415-421. doi: 10.1016/j.oftale.2020.09.019. Epub 2021 May 16.
To determine the prevalence and factors associated with the development of ocular hypertension and glaucoma, in patients undergoing penetrating keratoplasty, in the Eye Clinic of the city of Bogotá.
A retrospective cross-sectional study was conducted, and 130 eyes of patients undergoing penetrating keratoplasty were analyzed at the Eye Clinic in Bogotá, between January 2015 and August 2018. Demographic and clinical data were obtained, and it was determined by bivariate analysis, the association factors and the prevalence of the pathology under study.
Prevalence of ocular hypertension was 27.69% and glaucoma 10%. Average age 48.93 ± 18.63 years; higher frequency of presentation in men (61.5%). Statistically significant association factors were male sex (PR 2.59), presence of peripheral anterior synechiae (PR 1.83), history of trauma (PR 2.16), prior PK (PR 2.10) and graft failure (PR 2.04). Post-KP glaucoma only had statistically significant association with bullous keratopathy (PR 2.76).
Ocular hypertension and glaucoma had a high prevalence after penetrating keratoplasty, and the association factors were similar to those reported in other international studies. Knowing these factors, allows focusing surveillance and treatment in these patients to avoid blindness due to damage of the optic nerve or corneal graft.
在波哥大市的眼科诊所，确定接受穿透性角膜移植术的患者中发生眼压升高和青光眼的患病率及其相关因素。
进行了回顾性的横断面研究，分析了 2015 年 1 月至 2018 年 8 月期间在波哥大市眼科诊所接受穿透性角膜移植术的 130 只眼睛的患者数据。获取了人口统计学和临床数据，并通过双变量分析确定了该研究中病理的关联因素和患病率。
眼压升高的患病率为 27.69%，青光眼的患病率为 10%。平均年龄为 48.93 ± 18.63 岁；男性的就诊频率更高（61.5%）。具有统计学意义的关联因素包括男性（PR 2.59）、前房粘连（PR 1.83）、创伤史（PR 2.16）、先前的 PK（PR 2.10）和移植物失败（PR 2.04）。穿透性角膜移植术后青光眼仅与大泡性角膜病变（PR 2.76）具有统计学显著关联。
穿透性角膜移植术后，眼压升高和青光眼的患病率较高，且关联因素与其他国际研究报告的相似。了解这些因素，可以使我们能够专注于这些患者的监测和治疗，以避免因视神经或角膜移植物损伤导致的失明。
