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马的内侧近籽骨中体轴面的真菌性骨炎。

Fungal osteitis of the axial aspect of the mid body of the medial proximal sesamoid bone in a horse.

机构信息

Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1.

出版信息

Can Vet J. 2021 Aug;62(8):867-871.

PMID:34341602
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8281936/
Abstract

The satisfactory outcome of fungal osteitis in an 8-year-old American Quarter Horse is described. The horse was admitted with a grade 4 out of 5 lameness and exhibited metacarpophalangeal synovial effusion, indicative of a mild suppurative inflammation. Results of initial radiographic and ultrasonographic examination were unremarkable. Intra-articular anesthesia of the metacarpophalangeal joint allowed localization of the insult. It was not until day 6 of hospitalization when lytic changes on the axial aspect were observed on radiographic examination. Arthroscopic examination permitted identification and debridement of the affected bone. Fungal culture of the bone yielded spp. The horse was sound at the time of discharge after 12 days of hospitalization. No complications occurred in the post-operative period and the horse resumed his initial level of activity and competition in barrel racing. Key clinical message: To our knowledge, this is the first description of successful outcome of a fungal osteitis of the sesamoid bones following arthroscopic debridement. We hypothesize that the satisfactory outcome is associated with early recognition of the condition and aggressive debridement of the lesion arthroscopically.

摘要

描述了一例 8 岁美国夸特马的真菌性骨炎的满意治疗结果。该马因 4/5 级跛行而入院,表现为掌指关节滑膜积液,提示轻度化脓性炎症。最初的放射学和超声检查结果无明显异常。掌指关节的关节内麻醉有助于确定损伤部位。直到住院第 6 天,放射检查才观察到轴向的溶骨性改变。关节镜检查可识别和清除受影响的骨。骨的真菌培养结果为 spp。该马在住院 12 天后出院时恢复正常。术后无并发症发生,该马恢复了最初的活动水平,并在桶式赛马比赛中恢复了比赛。主要临床信息:据我们所知,这是首例经关节镜清创术成功治疗籽骨真菌性骨炎的病例描述。我们假设满意的结果与对病情的早期认识和积极的关节镜下病变清创有关。

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Fungal osteitis of the axial aspect of the mid body of the medial proximal sesamoid bone in a horse.马的内侧近籽骨中体轴面的真菌性骨炎。
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本文引用的文献

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Prevalence of Antibiotic-Resistant Pathogens in Culture-Proven Sepsis and Outcomes Associated With Inadequate and Broad-Spectrum Empiric Antibiotic Use.培养证实的脓毒症中抗生素耐药病原体的流行情况以及与经验性抗生素使用不足和广谱相关的结局。
JAMA Netw Open. 2020 Apr 1;3(4):e202899. doi: 10.1001/jamanetworkopen.2020.2899.
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Diversity of coelomycetous fungi in human infections: A 10-y experience of two European reference centres.人体感染后生真菌的多样性:两个欧洲参考中心的 10 年经验。
Fungal Biol. 2019 Apr;123(4):341-349. doi: 10.1016/j.funbio.2019.02.001. Epub 2019 Feb 14.
3
Comparison of conventional radiography and computed tomography as aids in the diagnosis of osteomyelitis in 11 foals.11例马驹中传统X线摄影与计算机断层扫描在骨髓炎诊断中的辅助作用比较
Aust Vet J. 2018 Jul;96(7):257-261. doi: 10.1111/avj.12710.
4
Cutaneous fungal infection in a renal transplantation patient due to a rare fungus belonging to order Pleosporales.一名肾移植患者因一种属于格孢腔菌目的罕见真菌而发生皮肤真菌感染。
Indian J Med Microbiol. 2015 Jan-Mar;33(1):165-7. doi: 10.4103/0255-0857.148435.
5
Axial osteitis of the proximal sesamoid bones and desmitis of the intersesamoidean ligament in the hindlimb of Friesian horses: review of 12 cases (2002-2012) and post-mortem analysis of the bone-ligament interface.弗里斯兰马后肢近籽骨轴向骨炎及籽骨间韧带腱炎:12例病例回顾(2002 - 2012年)及骨 - 韧带界面的尸检分析
BMC Vet Res. 2014 Nov 19;10:272. doi: 10.1186/s12917-014-0272-x.
6
Fungal osteomyelitis and septic arthritis.真菌感染性骨髓炎和化脓性关节炎。
J Am Acad Orthop Surg. 2014 Jun;22(6):390-401. doi: 10.5435/JAAOS-22-06-390.
7
Systemic inflammatory markers and aspiration cell count may not differentiate bacterial from fungal prosthetic infections.全身炎症标志物和抽吸细胞计数可能无法区分细菌性与真菌性人工关节感染。
Clin Orthop Relat Res. 2014 Nov;472(11):3291-4. doi: 10.1007/s11999-014-3631-9.
8
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J Am Vet Med Assoc. 2006 Nov 15;229(10):1607-11. doi: 10.2460/javma.229.10.1607.
9
Fungal arthritis and osteomyelitis.真菌性关节炎和骨髓炎。
Infect Dis Clin North Am. 2005 Dec;19(4):831-51. doi: 10.1016/j.idc.2005.08.004.
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Use of computed tomography angiography to evaluate the vascular anatomy of the distal portion of the forelimb of horses.使用计算机断层血管造影术评估马前肢远端的血管解剖结构。
Am J Vet Res. 2004 Oct;65(10):1409-20. doi: 10.2460/ajvr.2004.65.1409.