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干燥综合征患者的小唾液腺肿大

Minor salivary gland swelling in patient with Sjögren's syndrome.

作者信息

Takeda Y, Suzuki A, Kuroda M, Fujioka Y, Takayama K

机构信息

Department of Oral Pathology, School of Dentistry, Iwate Medical University, Japan.

出版信息

Acta Pathol Jpn. 1987 Oct;37(10):1603-9. doi: 10.1111/j.1440-1827.1987.tb02470.x.

Abstract

A case of Sjögren's syndrome with an unusual minor salivary gland swelling is reported. The patient was a 63-year-old female with a chief complaint of palatal swelling and dry mouth. Clinical examination revealed diffuse swelling of the hard palate and bilateral parotid regions, and sialographic examination of the parotid gland showed evidence of sialoangiectasia. Histopathological findings of the palatal and parotid lesions revealed intense lymphoid cell infiltration replacing the salivary gland parenchyma, and scattered epimyoepithelial islands throughout the lesions. Although it is well known that major salivary gland swelling caused by marked lymphoid cell infiltration is one of the common features in patients with Sjögren's syndrome, a similar swelling in the region of the minor salivary glands is not usually apparent.

摘要

报告了一例伴有不寻常小涎腺肿胀的干燥综合征病例。患者为一名63岁女性,主要症状为腭部肿胀和口干。临床检查发现硬腭和双侧腮腺区域弥漫性肿胀,腮腺造影检查显示有涎管扩张迹象。腭部和腮腺病变的组织病理学检查结果显示,密集的淋巴细胞浸润取代了涎腺实质,病变部位散在有肌上皮岛。虽然众所周知,显著的淋巴细胞浸润引起的大涎腺肿胀是干燥综合征患者的常见特征之一,但小涎腺区域的类似肿胀通常并不明显。

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