Tahririan Mohamad Ali, Nodushan Seyed Mohamad Hossein Tabatabaei, Farrokhi Mehrdad
Department of Orthopedics, Isfahan University of Medical Sciences, Isfahan, Iran.
Bone Joint and Related Tissues Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
J Res Med Sci. 2021 May 27;26:32. doi: 10.4103/jrms.JRMS_338_20. eCollection 2021.
We report an extremely rare case of multifocal bone disorder in a 3.5-year-old boy who appeared for left forearm and arm pain and multiple periods of fever with an unusual presentation of lymphoma/leukemia and highlight diagnostic challenges leading to a misdiagnosis, which was then diagnosed and treated for chronic recurrent multifocal osteomyelitis (CRMO). Based on a left arm biopsy and whole-body scans, he was eventually diagnosed with CRMO. Taken together, in this case, we noticed a notable amelioration after a 5-month treatment with nonsteroidal anti-inflammatory drugs on multiple bone pains.
我们报告了一例极为罕见的3.5岁男孩多灶性骨病病例，该男孩因左前臂和手臂疼痛以及多次发热前来就诊，其表现为淋巴瘤/白血病的不寻常症状，并强调了导致误诊的诊断挑战，随后该病例被诊断为慢性复发性多灶性骨髓炎（CRMO）并接受治疗。基于左臂活检和全身扫描，他最终被诊断为CRMO。综合来看，在该病例中，我们注意到在使用非甾体抗炎药对多处骨痛进行5个月的治疗后有明显改善。
