经皮冠状动脉介入治疗中血小板功能及基因检测指导双重抗血小板治疗的不确定性 - Suppr

Uncertainties about platelet function and genetic testing for guiding dual antiplatelet therapy in percutaneous coronary intervention.

作者信息

Condello Francesco

机构信息

Department of Biomedical Sciences, Humanitas University, via Rita Levi Montalcini 4, Pieve Emanuele, 20090, Milano, Italy.

IRCCS Humanitas Research Hospital, via Alessandro Manzoni 56, Rozzano, 20089, Milano, Italy.

出版信息

J Thromb Thrombolysis. 2022 Feb;53(2):514-516. doi: 10.1007/s11239-021-02543-y. Epub 2021 Aug 4.

DOI:10.1007/s11239-021-02543-y

PMID:34347203

Abstract

摘要

相似文献

Uncertainties about platelet function and genetic testing for guiding dual antiplatelet therapy in percutaneous coronary intervention.经皮冠状动脉介入治疗中血小板功能及基因检测指导双重抗血小板治疗的不确定性

J Thromb Thrombolysis. 2022 Feb;53(2):514-516. doi: 10.1007/s11239-021-02543-y. Epub 2021 Aug 4.

Dual-Antiplatelet Therapy After Percutaneous Coronary Intervention: How Short Is Too Short?经皮冠状动脉介入治疗后的双联抗血小板治疗：多短才算太短？

J Am Heart Assoc. 2023 Jan 17;12(2):e028775. doi: 10.1161/JAHA.122.028775. Epub 2023 Jan 16.

Meta-Analysis of One-Month Dual Antiplatelet Therapy Versus Standard Dual Antiplatelet Therapy in Patients Undergoing Percutaneous Coronary Intervention.经皮冠状动脉介入治疗患者中为期1个月的双重抗血小板治疗与标准双重抗血小板治疗的Meta分析

Am J Cardiol. 2022 Mar 1;166:138-140. doi: 10.1016/j.amjcard.2021.11.035. Epub 2021 Dec 31.

Meta-Analysis of Brief Dual-Antiplatelet Therapy Duration After Percutaneous Coronary Intervention.经皮冠状动脉介入治疗后短期双联抗血小板治疗持续时间的Meta分析

Am J Cardiol. 2022 Jul 1;174:182-184. doi: 10.1016/j.amjcard.2022.03.045. Epub 2022 Apr 30.

Updated Expert Consensus Statement on Platelet Function and Genetic Testing for Guiding P2Y Receptor Inhibitor Treatment in Percutaneous Coronary Intervention.更新的血小板功能和基因检测指导经皮冠状动脉介入治疗中 P2Y 受体抑制剂治疗的专家共识声明。

JACC Cardiovasc Interv. 2019 Aug 26;12(16):1521-1537. doi: 10.1016/j.jcin.2019.03.034. Epub 2019 Jun 12.

Pharmacodynamic Comparison of Ticagrelor Monotherapy Versus Ticagrelor and Aspirin in Patients After Percutaneous Coronary Intervention: The TEMPLATE (Ticagrelor Monotherapy and Platelet Reactivity) Randomized Controlled Trial.经皮冠状动脉介入治疗后替格瑞洛单药治疗与替格瑞洛联合阿司匹林治疗患者的药效学比较： TEMPLATE（替格瑞洛单药治疗和血小板反应性）随机对照试验。

J Am Heart Assoc. 2020 Dec 15;9(24):e016495. doi: 10.1161/JAHA.120.016495. Epub 2020 Dec 11.

Individualized dual antiplatelet therapy based on platelet function testing in patients undergoing percutaneous coronary intervention: a meta-analysis of randomized controlled trials.经皮冠状动脉介入治疗患者基于血小板功能检测的个体化双联抗血小板治疗：随机对照试验的荟萃分析

BMC Cardiovasc Disord. 2017 Jun 15;17(1):157. doi: 10.1186/s12872-017-0582-6.

Patterns and Outcomes of Dual Antiplatelet Therapy Discontinuation After Percutaneous Coronary Intervention.经皮冠状动脉介入治疗后双联抗血小板治疗中断的模式与结局

JACC Cardiovasc Interv. 2022 Apr 25;15(8):807-809. doi: 10.1016/j.jcin.2022.02.048.

Platelet function testing guided antiplatelet therapy reduces cardiovascular events in Chinese patients with ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention: The PATROL study.血小板功能检测指导抗血小板治疗降低中国 ST 段抬高型心肌梗死经皮冠状动脉介入治疗患者的心血管事件：PATROL 研究。

Catheter Cardiovasc Interv. 2020 Feb;95 Suppl 1:598-605. doi: 10.1002/ccd.28712. Epub 2020 Jan 20.

The Challenges of Percutaneous Coronary Intervention and Dual Antiplatelet Therapy in Cancer Patients.癌症患者经皮冠状动脉介入治疗和双重抗血小板治疗的挑战

Cardiovasc Revasc Med. 2022 Sep;42:107-108. doi: 10.1016/j.carrev.2022.06.016. Epub 2022 Jun 18.

引用本文的文献

Safety and Efficacy of CYP2C19 Genotype-Guided Escalation of P2Y Inhibitor Therapy After Percutaneous Coronary Intervention in Chronic Kidney Disease: a Post Hoc Analysis of the TAILOR-PCI Study.经皮冠状动脉介入治疗后基于 CYP2C19 基因型指导的 P2Y 抑制剂治疗剂量递增在慢性肾脏病患者中的疗效和安全性：TAILOR-PCI 研究的事后分析。

Cardiovasc Drugs Ther. 2024 Jun;38(3):447-457. doi: 10.1007/s10557-022-07392-2. Epub 2022 Nov 29.

Walking the Line with Ticagrelor: Meta-Analysis Comparing the Safety and Efficacy of Ticagrelor Monotherapy after a Short Course of Ticagrelor-Based Dual Antiplatelet Therapy versus Standard Therapy in Complex Percutaneous Coronary Intervention.替格瑞洛的权衡：比较替格瑞洛为基础的短期双联抗血小板治疗后替格瑞洛单药治疗与标准治疗在复杂经皮冠状动脉介入治疗中的安全性和有效性的荟萃分析

J Clin Med. 2021 Nov 24;10(23):5506. doi: 10.3390/jcm10235506.

本文引用的文献

Guided versus standard antiplatelet therapy in patients undergoing percutaneous coronary intervention: a systematic review and meta-analysis.经皮冠状动脉介入治疗患者中接受指导与标准抗血小板治疗的比较：系统评价和荟萃分析。

Lancet. 2021 Apr 17;397(10283):1470-1483. doi: 10.1016/S0140-6736(21)00533-X.

JACC Cardiovasc Interv. 2019 Aug 26;12(16):1521-1537. doi: 10.1016/j.jcin.2019.03.034. Epub 2019 Jun 12.

ACC/AHA Versus ESC Guidelines on Dual Antiplatelet Therapy: JACC Guideline Comparison.ACC/AHA 与 ESC 双重抗血小板治疗指南：JACC 指南比较。

J Am Coll Cardiol. 2018 Dec 11;72(23 Pt A):2915-2931. doi: 10.1016/j.jacc.2018.09.057.

Platelet function monitoring to adjust antiplatelet therapy in elderly patients stented for an acute coronary syndrome (ANTARCTIC): an open-label, blinded-endpoint, randomised controlled superiority trial.血小板功能监测以调整急性冠状动脉综合征支架置入老年患者的抗血小板治疗（南极洲研究）：一项开放标签、盲终点、随机对照优势试验

Lancet. 2016 Oct 22;388(10055):2015-2022. doi: 10.1016/S0140-6736(16)31323-X. Epub 2016 Aug 28.

Bleeding and stent thrombosis on P2Y12-inhibitors: collaborative analysis on the role of platelet reactivity for risk stratification after percutaneous coronary intervention.抗血小板治疗致出血和支架血栓形成：经皮冠状动脉介入治疗后血小板反应性对危险分层作用的协作分析。

Eur Heart J. 2015 Jul 14;36(27):1762-71. doi: 10.1093/eurheartj/ehv104. Epub 2015 Apr 20.

Point-of-care genetic testing for personalisation of antiplatelet treatment (RAPID GENE): a prospective, randomised, proof-of-concept trial.即时检测指导抗血小板治疗个体化的研究（RAPID GENE）：一项前瞻性、随机、概念验证试验。

Lancet. 2012 May 5;379(9827):1705-11. doi: 10.1016/S0140-6736(12)60161-5. Epub 2012 Mar 29.

Double-blind study of the safety of clopidogrel with and without a loading dose in combination with aspirin compared with ticlopidine in combination with aspirin after coronary stenting : the clopidogrel aspirin stent international cooperative study (CLASSICS).冠状动脉支架置入术后氯吡格雷联合阿司匹林负荷剂量与非负荷剂量安全性的双盲研究：与噻氯匹定联合阿司匹林比较：氯吡格雷阿司匹林支架国际合作研究（CLASSICS）

Circulation. 2000 Aug 8;102(6):624-9. doi: 10.1161/01.cir.102.6.624.

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Uncertainties about platelet function and genetic testing for guiding dual antiplatelet therapy in percutaneous coronary intervention.

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