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腹腔镜脾切除术和脾-肾静脉分流术治疗蛋白 S 缺乏症患者门静脉血栓形成所致门静脉高压症。

Laparoscopic splenectomy and proximal splenorenal shunt for portal hypertension due to portal vein thrombosis in a patient with protein S deficiency.

机构信息

Department of Gastroenterology, Hospital Cayetano Heredia. Lima, Peru.

Department of Surgery, Clínica Angloamericana. Lima, Peru.

出版信息

Rev Gastroenterol Peru. 2021 Jan-Mar;41(1):48-51.

PMID:34347772
Abstract

Portal vein thrombosis (PVT) is a rare condition in the general population that develops serious complications if left untreated for long time. We present a case of a 29-year-old woman who developed PVT due to protein S deficiency versus neonatal funiculitis. Over time, the patient developed upper gastrointestinal bleeding due to esophageal varices and hypersplenism with splenic sequestration that caused minor bleeding episodes. Laparoscopic splenectomy and proximal splenorenal shunt with distal pancreatectomy due to aneurysmal dilatations of the splenic artery were successfully performed to avoid mayor progression of portal hypertension. Patient was discharged with indefinite anticoagulation and after surgery platelets raised up to 200x103/mm3. Laparoscopic splenectomy and proximal splenorenal shunt for portal hypertension due to portal vein thrombosis is an adequate surgery procedure which should be applied in these medical cases.

摘要

门静脉血栓形成(PVT)在普通人群中较为罕见,如果长期未经治疗,会引发严重并发症。我们报告了一例 29 岁女性患者,因蛋白 S 缺乏合并新生儿精索炎导致 PVT。随着时间的推移,患者因食管静脉曲张和脾功能亢进导致脾功能亢进而出现上消化道出血,脾功能亢进导致脾内出血。由于脾动脉动脉瘤样扩张,成功进行了腹腔镜脾切除术和近端脾肾分流术,并进行了远端胰腺切除术,以避免门静脉高压症的进一步恶化。患者出院时未进行抗凝治疗,术后血小板升至 200x103/mm3。腹腔镜脾切除术和近端脾肾分流术治疗门静脉血栓形成引起的门静脉高压症是一种有效的手术方法,适用于此类医疗病例。

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