9-芴甲氧羰基焦谷氨酸，一种谷氨酸与9-芴甲基氯甲酸酯衍生化的副产物：一则警示
9-Fluorenylmethoxycarbonylpyroglutamate, a side-product of derivatization of glutamate with 9-fluorenylmethyl chloroformate: a warning.
作者信息
Keller H J, Quang Do K, Zollinger M, Winterhalter K H, Cuénod M
机构信息
Institut für Hirnforschung, Universität Zürich, Switzerland.
出版信息
Anal Biochem. 1987 Nov 1;166(2):431-4. doi: 10.1016/0003-2697(87)90595-1.
PMID:3434783
Abstract
9-Fluorenylmethyl chloroformate derivatization is widely used for determinations of amino acids in biological material. The derivatization of glutamate leads to the formation of 9-fluorenylmethoxycarbonylpyroglutamate as a side-product, which is thus a methodological artifact.
摘要
9-芴甲基氯甲酸酯衍生化法广泛用于生物材料中氨基酸的测定。谷氨酸的衍生化会产生一种副产物9-芴甲氧羰基焦谷氨酸，因此这是一种方法学假象。
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