Faculty of Medicine, University of Fortaleza, Fortaleza, Brazil.
Poison Control Center, Instituto Doutor Jose Frota Hospital, Fortaleza, Brazil.
Contrib Nephrol. 2021;199:244-251. doi: 10.1159/000517725. Epub 2021 Aug 4.
Snakebite-related acute kidney injury (AKI) is mainly caused by bites from the Viperidae family which are common snakes worldwide. It is a frequent and potentially fatal clinical complication. Coagulation abnormalities are usually present and are most likely to contribute to AKI development. A better comprehension of AKI pathogenesis following the toxicsyndrome may improve patient management by primary healthcare providers, allowing earlier diagnosis and treatment. This chapter highlights the main studies about snakevenom-related AKI, the most common snakes around the world, and the respective mechanisms of AKI.
蛇伤相关性急性肾损伤(AKI)主要由蝰蛇科家族的毒蛇咬伤引起,这些毒蛇在全球范围内很常见。它是一种常见且可能致命的临床并发症。通常存在凝血异常,并且很可能促成 AKI 的发生。通过初级保健提供者更好地了解毒素综合征后的 AKI 发病机制,可以改善患者的管理,从而更早地进行诊断和治疗。本章重点介绍了与蛇毒相关的 AKI 的主要研究、世界各地最常见的蛇以及各自的 AKI 机制。