Internal and Subintensive Medicine Department, Azienda Ospedaliero-Universitaria "Ospedali Riuniti,", Ancona, Italy.
Neurological Clinic, Azienda Ospedaliero-Universitaria "Ospedali Riuniti,", Ancona, Italy.
Med Princ Pract. 2021;30(6):501-507. doi: 10.1159/000518261. Epub 2021 Jul 7.
Chronic respiratory disorders represent a world epidemic. Their incidence and prevalence in the world population is increasing, and especially among elderly subjects, they are commonly associated with other pathologies, often generating a status of high clinical complexity. Neurology, internal medicine, and pneumology specialists should be aware of the common background of these disorders in order to treat correctly the patient's comorbid state and optimize the treatment considering potential overlaps. In this review, we aimed to focus on the relationships between chronic respiratory disorders and chronic neurodegenerative diseases at different levels; we review the shared risk factors and the interactions between disorders, the indications to explore respiratory function in neurodegenerative diseases, pathology-pathology and drug-pathology interactions in patients affected by both chronic neurologic and respiratory diseases.
慢性呼吸系统疾病是一种全球性流行疾病。其在世界人群中的发病率和患病率不断增加，特别是在老年人群中，这些疾病常与其他疾病相关，往往导致高度复杂的临床状况。神经病学、内科和肺病学专家应了解这些疾病的常见背景，以便正确治疗患者的合并症，并考虑潜在的重叠因素优化治疗。在本次综述中，我们旨在关注慢性呼吸系统疾病和慢性神经退行性疾病在不同层面的关系；我们回顾了共同的危险因素和疾病之间的相互作用、在神经退行性疾病中探索呼吸功能的指征、在患有慢性神经和呼吸系统疾病的患者中，病理学-病理学和药物-病理学的相互作用。
