鼻息肉与心脏功能的关系。
Nasal Polyposis and Its Association with Cardiac Functions.
机构信息
Department of Otolaryngology-Head & Neck Surgery (ENT), Indira Gandhi Medical College, Shimla, India.
Department of Radiodiagnosis, Indira Gandhi Medical College, Shimla, India.
出版信息
Med Princ Pract. 2021;30(6):522-526. doi: 10.1159/000517976. Epub 2021 Jun 23.
OBJECTIVE
The aim of the study was to ascertain the effect of nasal polyposis on cardiac functions.
MATERIAL AND METHODS
A prospective randomized interventional open-label endpoint-controlled study was conducted in an academic tertiary care hospital. Thirty-one patients with chronic rhinosinusitis with nasal polyposis were enrolled and administered fluticasone furoate nasal spray for 3 weeks before randomly segregation into surgical or medical group. The treatment continued for 3 months in both groups. The SNOT-22 (Sino-Nasal Outcome Test-22) score, polyp grade, and right ventricular and pulmonary arterial functions were recorded in both groups before and after 3 months of the intervention.
RESULTS
Both groups had significant improvement in SNOT-22 scores after 3 months of intervention. Both groups showed improvement in cardiac functions, but statistical significance was found only in subjects who underwent surgery.
CONCLUSION
Nasal polyp affects cardiac functions, and this needs further evaluation and research through studies on large samples.
目的
本研究旨在确定鼻息肉对心脏功能的影响。
材料与方法
在一所学术性三级护理医院进行了一项前瞻性随机干预性开放标签终点对照研究。招募了 31 例慢性鼻-鼻窦炎伴鼻息肉患者，在随机分为手术组或药物组之前，给予糠酸氟替卡松鼻喷雾剂治疗 3 周。两组均继续治疗 3 个月。在干预后 3 个月时，记录两组的 SNOT-22（鼻-鼻窦结局测试-22）评分、息肉分级以及右心室和肺动脉功能。
结果
两组患者在干预 3 个月后 SNOT-22 评分均显著改善。两组患者的心脏功能均有所改善，但仅在接受手术的患者中具有统计学意义。
结论
鼻息肉会影响心脏功能，需要通过大样本研究进一步评估和研究。
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