Reproductive failure and pericentric inversion in man.

作者信息

Gabriel-Robez O, Ratomponirina C, Croquette M, Maetz J L, Couturier J, Rumpler Y

机构信息

Institut d'Embryologie, Faculté de Médecine, Strasbourg, France.

出版信息

Andrologia. 1987 Nov-Dec;19(6):662-9. doi: 10.1111/j.1439-0272.1987.tb01924.x.

Pachytene analysis was carried out on an infertile man heterozygous for a pericentric inversion of chromosome 6. The synaptic behavior of the bivalent 6 inversion was analyzed using electron microscopy in silver stained surface microspread of the inversion-bearing spermatocytes. Possible mechanisms of the sterilizing effect caused by the autosomal inversion are discussed.