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用卡介苗接种控制老年人的炎症。

Controlling inflammation in the elderly with BCG vaccination.

机构信息

Radboud Center for Infectious Diseases and Department of Internal Medicine, Radboud University Medical Center, Nijmegen, Netherlands.

Department of Computational Biology for Individualised Infection Medicine, Centre for Individualised Infection Medicine (CiiM), a joint venture between the Helmholtz-Centre for Infection Research (HZI) and the Hannover Medical School (MHH), Hannover, Germany.

出版信息

Sci Adv. 2021 Aug 4;7(32). doi: 10.1126/sciadv.abk1668. Print 2021 Aug.

DOI:10.1126/sciadv.abk1668
PMID:34348906
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8336952/
Abstract

The tuberculosis vaccine BCG may protect against inflammation in the elderly as well as offer an option for protection from SARS-CoV-2 in developing countries.

摘要

卡介苗（BCG）疫苗可能有助于预防老年人的炎症，也为发展中国家预防 SARS-CoV-2 提供了一种选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f02b/8336952/b473e5c885d2/abk1668-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f02b/8336952/b473e5c885d2/abk1668-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f02b/8336952/b473e5c885d2/abk1668-F1.jpg

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本文引用的文献

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2
COVID-19 vaccine efficacy and effectiveness-the elephant (not) in the room.新冠病毒疫苗的效力和效果——房间里的（并非）大象。
Lancet Microbe. 2021 Jul;2(7):e279-e280. doi: 10.1016/S2666-5247(21)00069-0. Epub 2021 Apr 20.
3
The BCG Vaccine for COVID-19: First Verdict and Future Directions.《COVID-19 用卡介苗疫苗：初步结论和未来方向》
Signal Transduct Target Ther. 2022 Jan 27;7(1):26. doi: 10.1038/s41392-022-00884-5.
Front Immunol. 2021 Mar 8;12:632478. doi: 10.3389/fimmu.2021.632478. eCollection 2021.
4
COVID-19 and the human innate immune system.新型冠状病毒肺炎与人类固有免疫系统。
Cell. 2021 Apr 1;184(7):1671-1692. doi: 10.1016/j.cell.2021.02.029. Epub 2021 Feb 16.
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Inflammaging as a link between autoimmunity and cardiovascular disease: the case of rheumatoid arthritis.炎症性衰老作为自身免疫和心血管疾病之间的联系：以类风湿关节炎为例。
RMD Open. 2021 Jan;7(1). doi: 10.1136/rmdopen-2020-001470.
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Activate: Randomized Clinical Trial of BCG Vaccination against Infection in the Elderly.激活：卡介苗疫苗接种预防老年人感染的随机临床试验。
Cell. 2020 Oct 15;183(2):315-323.e9. doi: 10.1016/j.cell.2020.08.051. Epub 2020 Sep 1.
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