Pak Hyeon-Ju, Choi Ha-Neul, Lee Hong-Chan, Yim Jung-Eun
Department of Food and Nutrition, Changwon National University, Changwon 51140, Korea.
Clinic B, Seoul 06035, Korea.
Nutr Res Pract. 2021 Aug;15(4):456-467. doi: 10.4162/nrp.2021.15.4.456. Epub 2021 Feb 8.
BACKGROUND/OBJECTIVES: The prevalence of morbid obesity in Korean women has consistently been increasing, while the overall prevalence rate of obesity in Korean women seems to be stable. In addition to bariatric surgery, intragastric balloons (IGBs), as a nonsurgical therapy, have been reported to be effective in weight loss. However, the beneficial effects of IGB in Korean women with obesity have not been fully investigated. The aim of this study was to evaluate the changes in fat mass in Korean women with obesity who had undergone IGB treatment for 6 mon.
SUBJECTS/METHODS: Seventy-four women with obesity (body mass index [BMI] ≥ 25.0 kg/m) were recruited. Clinical data, including general information, comorbidities with obesity, anthropometric data, and changes in the body fat composition before and after IGB treatment, were obtained from the subjects.
Most subjects had one or more comorbidities, such as osteoarthropathy and woman's disease, and had poor eating behaviors, including irregular mealtimes, eating quickly, and frequent overeating. Body composition measurements showed that weight, fat mass, and waist-hip circumference ratio decreased significantly at 6 mon after IGB treatment. In particular, women with morbid obesity (BMI ≥ 30 kg/m) showed 33% excess weight loss. There was no significant difference in skeletal muscle mass and mineral contents after IGB treatment.
This study suggested that 6 mon of IGB treatment can be a beneficial treatment for obesity without muscle mass and bone mineral loss.
背景/目的：韩国女性中病态肥胖的患病率一直在持续上升，而韩国女性肥胖的总体患病率似乎保持稳定。除了减肥手术外，胃内气球（IGB）作为一种非手术治疗方法，据报道在减肥方面是有效的。然而，IGB对韩国肥胖女性的有益作用尚未得到充分研究。本研究的目的是评估接受IGB治疗6个月的韩国肥胖女性的脂肪量变化。
对象/方法：招募了74名肥胖女性（体重指数[BMI]≥25.0kg/m）。从受试者处获取临床数据，包括一般信息、肥胖合并症、人体测量数据以及IGB治疗前后身体脂肪成分的变化。
大多数受试者有一种或多种合并症，如骨关节炎和妇科疾病，并且有不良的饮食行为，包括用餐时间不规律、进食快和频繁暴饮暴食。身体成分测量显示，IGB治疗6个月后体重、脂肪量和腰臀围比显著下降。特别是病态肥胖（BMI≥30kg/m）的女性体重减轻了33%。IGB治疗后骨骼肌质量和矿物质含量没有显著差异。
本研究表明，6个月的IGB治疗对于肥胖症可能是一种有益的治疗方法，且不会导致肌肉量和骨矿物质流失。
