Han Sangbin
Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Anesth Pain Med (Seoul). 2021 Jul;16(3):225-231. doi: 10.17085/apm.21063. Epub 2021 Jul 22.
When tissue injury results in breakage, platelets are not only involved in plug formation and wound sealing, but they also play an important role throughout the tissue recovery process. Specifically, platelets accumulate at the site of injury and release a large number of biologically active mediators at injury sites, which initiate or modulate damaged tissue regeneration. Moreover, extensive experimental evidence has elucidated the involvement of platelets in tumor growth and metastasis. As such, this mini-review aimed to highlight the relatively lesser known functions of platelets.
当组织损伤导致破裂时，血小板不仅参与血栓形成和伤口愈合，而且在整个组织恢复过程中也发挥着重要作用。具体而言，血小板在损伤部位聚集，并在损伤部位释放大量生物活性介质，这些介质启动或调节受损组织的再生。此外，大量实验证据表明血小板参与肿瘤生长和转移。因此，本综述旨在突出血小板相对鲜为人知的功能。
