Wong V, Yeung C Y
Department of Paediatrics, University of Hong Kong, Queen Mary Hospital.
Aust Paediatr J. 1987 Dec;23(6):339-42. doi: 10.1111/j.1440-1754.1987.tb00286.x.
Fifty-seven cases satisfying criteria of the diagnosis of acute viral encephalitis were studied. They were divided into two groups: Group 1 (presumed), 48 cases; Group 2 (postinfectious), nine cases. A possible association of viral aetiology was found in 26%. Viruses isolated were: influenza (3 cases), Coxsackie virus (2), adenovirus (2), mixed cytomegalovirus and adenovirus and herpes simplex viruses (1 case each). The mortality rate was 28%. Among the 41 survivors, 76% were completely normal and 24% had neurological sequelae with focal neurological deficit in 29%; personality changes in 6%; moderate mental retardation in 2%; severe mental retardation in 4%; hyperactivity in 4% and epilepsy in 4%. The best predictors to unfavourable outcome were the rapid rate of deterioration in conscious level after admission and the age of the patients.
对57例符合急性病毒性脑炎诊断标准的病例进行了研究。这些病例被分为两组：第1组（疑似），48例；第2组（感染后），9例。发现26%的病例可能与病毒病因有关。分离出的病毒有：流感病毒（3例）、柯萨奇病毒（2例）、腺病毒（2例）、巨细胞病毒与腺病毒混合感染以及单纯疱疹病毒（各1例）。死亡率为28%。在41名幸存者中，76%完全正常，24%有神经后遗症，其中29%有局灶性神经功能缺损；6%有人格改变；2%有中度智力障碍；4%有重度智力障碍；4%有多动症；4%有癫痫。入院后意识水平快速恶化以及患者年龄是不良预后的最佳预测因素。
